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PKG II secreted via the classical endoplasmic reticulum-Golgi apparatus secretory pathway blocks the activation of EGFR through phosporalting its threonine 406 and has an anti-tumor effect.
Wu Y, Wu M, Wang Z, Pang J, Zhu M, Lan T, Yao X, Qian H, Lin X, Jiang L, Tao Y, Zhang Y, Chen Y. Wu Y, et al. Among authors: yao x. Front Biosci (Landmark Ed). 2022 Feb 11;27(2):53. doi: 10.31083/j.fbl2702053. Front Biosci (Landmark Ed). 2022. PMID: 35226996 Free article.
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