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Page 1
Effective targeting of breast cancer stem cells by combined inhibition of Sam68 and Rad51.
Turdo A, Gaggianesi M, Di Franco S, Veschi V, D'Accardo C, Porcelli G, Lo Iacono M, Pillitteri I, Verona F, Militello G, Zippo A, Poli V, Fagnocchi L, Beyes S, Stella S, Lattanzio R, Faldetta N, Lentini VL, Porcasi R, Pistone G, Bongiorno MR, Stassi G, De Maria R, Todaro M. Turdo A, et al. Among authors: lattanzio r. Oncogene. 2022 Apr;41(15):2196-2209. doi: 10.1038/s41388-022-02239-4. Epub 2022 Feb 25. Oncogene. 2022. PMID: 35217791 Free PMC article.
Upregulation of Trop-2 quantitatively stimulates human cancer growth.
Trerotola M, Cantanelli P, Guerra E, Tripaldi R, Aloisi AL, Bonasera V, Lattanzio R, de Lange R, Weidle UH, Piantelli M, Alberti S. Trerotola M, et al. Among authors: lattanzio r. Oncogene. 2013 Jan 10;32(2):222-33. doi: 10.1038/onc.2012.36. Epub 2012 Feb 20. Oncogene. 2013. PMID: 22349828
The Trop-2 signalling network in cancer growth.
Guerra E, Trerotola M, Aloisi AL, Tripaldi R, Vacca G, La Sorda R, Lattanzio R, Piantelli M, Alberti S. Guerra E, et al. Among authors: lattanzio r. Oncogene. 2013 Mar 21;32(12):1594-600. doi: 10.1038/onc.2012.151. Epub 2012 May 7. Oncogene. 2013. PMID: 22562244
miR-205-5p-mediated downregulation of ErbB/HER receptors in breast cancer stem cells results in targeted therapy resistance.
De Cola A, Volpe S, Budani MC, Ferracin M, Lattanzio R, Turdo A, D'Agostino D, Capone E, Stassi G, Todaro M, Di Ilio C, Sala G, Piantelli M, Negrini M, Veronese A, De Laurenzi V. De Cola A, et al. Among authors: lattanzio r. Cell Death Dis. 2015 Jul 16;6(7):e1823. doi: 10.1038/cddis.2015.192. Cell Death Dis. 2015. PMID: 26181203 Free PMC article.
GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine.
Ferro R, Adamska A, Lattanzio R, Mavrommati I, Edling CE, Arifin SA, Fyffe CA, Sala G, Sacchetto L, Chiorino G, De Laurenzi V, Piantelli M, Sansom OJ, Maffucci T, Falasca M. Ferro R, et al. Among authors: lattanzio r. Oncogene. 2018 Dec;37(49):6368-6382. doi: 10.1038/s41388-018-0390-1. Epub 2018 Jul 30. Oncogene. 2018. PMID: 30061636
The transcriptional terminator XRN2 and the RNA-binding protein Sam68 link alternative polyadenylation to cell cycle progression in prostate cancer.
Pieraccioli M, Caggiano C, Mignini L, Zhong C, Babini G, Lattanzio R, Di Stasi S, Tian B, Sette C, Bielli P. Pieraccioli M, et al. Among authors: lattanzio r. Nat Struct Mol Biol. 2022 Nov;29(11):1101-1112. doi: 10.1038/s41594-022-00853-0. Epub 2022 Nov 7. Nat Struct Mol Biol. 2022. PMID: 36344846 Free PMC article.
An ErbB-3 antibody, MP-RM-1, inhibits tumor growth by blocking ligand-dependent and independent activation of ErbB-3/Akt signaling.
Sala G, Traini S, D'Egidio M, Vianale G, Rossi C, Piccolo E, Lattanzio R, Piantelli M, Tinari N, Natali PG, Muraro R, Iacobelli S; Consorzio Interuniversitario Nazionale per la Bio-Oncologia. Sala G, et al. Among authors: lattanzio r. Oncogene. 2012 Mar 8;31(10):1275-86. doi: 10.1038/onc.2011.322. Epub 2011 Aug 8. Oncogene. 2012. PMID: 21822299
Overexpression of activated phospholipase Cγ1 is a risk factor for distant metastases in T1-T2, N0 breast cancer patients undergoing adjuvant chemotherapy.
Lattanzio R, Marchisio M, La Sorda R, Tinari N, Falasca M, Alberti S, Miscia S, Ercolani C, Di Benedetto A, Perracchio L, Melucci E, Iacobelli S, Mottolese M, Natali PG, Piantelli M; CINBO (Consorzio Interuniversitario Nazionale per Bio-Oncologia). Lattanzio R, et al. Int J Cancer. 2013 Mar 1;132(5):1022-31. doi: 10.1002/ijc.27751. Epub 2012 Sep 1. Int J Cancer. 2013. PMID: 22847294
Trop-2, Na+/K+ ATPase, CD9, PKCα, cofilin assemble a membrane signaling super-complex that drives colorectal cancer growth and invasion.
Guerra E, Relli V, Ceci M, Tripaldi R, Simeone P, Aloisi AL, Pantalone L, La Sorda R, Lattanzio R, Sacchetti A, Havas K, Guarnieri S, Vergara D, Fournier I, Salzet M, Tinari N, Piantelli M, Trerotola M, Alberti S. Guerra E, et al. Among authors: lattanzio r. Oncogene. 2022 Mar;41(12):1795-1808. doi: 10.1038/s41388-022-02220-1. Epub 2022 Feb 7. Oncogene. 2022. PMID: 35132180
High expression of 90K (Mac-2 BP) is associated with poor survival in node-negative breast cancer patients not receiving adjuvant systemic therapies.
Tinari N, Lattanzio R, Querzoli P, Natoli C, Grassadonia A, Alberti S, Hubalek M, Reimer D, Nenci I, Bruzzi P, Piantelli M, Iacobelli S; Consorzio Interuniversitario Nazionale per la Bio-Oncologia (CINBO). Tinari N, et al. Among authors: lattanzio r. Int J Cancer. 2009 Jan 15;124(2):333-8. doi: 10.1002/ijc.23970. Int J Cancer. 2009. PMID: 18942707
227 results