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A preclinical model of patient-derived cerebrospinal fluid circulating tumor cells for experimental therapeutics in leptomeningeal disease from melanoma.
Law V, Chen Z, Vena F, Smalley I, Macaulay R, Evernden BR, Tran N, Pina Y, Puskas J, Caceres G, Bayle S, Johnson J, Liu JKC, Etame A, Vogelbaum M, Rodriguez P, Duckett D, Czerniecki B, Chen A, Smalley KSM, Forsyth PA. Law V, et al. Among authors: forsyth pa. Neuro Oncol. 2022 Oct 3;24(10):1673-1686. doi: 10.1093/neuonc/noac054. Neuro Oncol. 2022. PMID: 35213727 Free PMC article.
Treating brain tumor-initiating cells using a combination of myxoma virus and rapamycin.
Zemp FJ, Lun X, McKenzie BA, Zhou H, Maxwell L, Sun B, Kelly JJ, Stechishin O, Luchman A, Weiss S, Cairncross JG, Hamilton MG, Rabinovich BA, Rahman MM, Mohamed MR, Smallwood S, Senger DL, Bell J, McFadden G, Forsyth PA. Zemp FJ, et al. Among authors: forsyth pa. Neuro Oncol. 2013 Jul;15(7):904-20. doi: 10.1093/neuonc/not035. Epub 2013 Apr 12. Neuro Oncol. 2013. PMID: 23585629 Free PMC article.
Novel treatments for melanoma brain metastases.
Kenchappa RS, Tran N, Rao NG, Smalley KS, Gibney GT, Sondak VK, Forsyth PA. Kenchappa RS, et al. Among authors: forsyth pa. Cancer Control. 2013 Oct;20(4):298-306. doi: 10.1177/107327481302000407. Cancer Control. 2013. PMID: 24077406 Free article. Review.
In vitro screen of a small molecule inhibitor drug library identifies multiple compounds that synergize with oncolytic myxoma virus against human brain tumor-initiating cells.
McKenzie BA, Zemp FJ, Pisklakova A, Narendran A, McFadden G, Lun X, Kenchappa RS, Kurz EU, Forsyth PA. McKenzie BA, et al. Among authors: forsyth pa. Neuro Oncol. 2015 Aug;17(8):1086-94. doi: 10.1093/neuonc/nou359. Epub 2015 Jan 20. Neuro Oncol. 2015. PMID: 25605818 Free PMC article.
M011L-deficient oncolytic myxoma virus induces apoptosis in brain tumor-initiating cells and enhances survival in a novel immunocompetent mouse model of glioblastoma.
Pisklakova A, McKenzie B, Zemp F, Lun X, Kenchappa RS, Etame AB, Rahman MM, Reilly K, Pilon-Thomas S, McFadden G, Kurz E, Forsyth PA. Pisklakova A, et al. Among authors: forsyth pa. Neuro Oncol. 2016 Aug;18(8):1088-1098. doi: 10.1093/neuonc/now006. Epub 2016 Mar 8. Neuro Oncol. 2016. PMID: 26962017 Free PMC article.
225 results