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Group 1 ILCs regulate T cell-mediated liver immunopathology by controlling local IL-2 availability.
Fumagalli V, Venzin V, Di Lucia P, Moalli F, Ficht X, Ambrosi G, Giustini L, Andreata F, Grillo M, Magini D, Ravà M, Friedrich C, Fontenot JD, Bousso P, Gilmore SA, Khan S, Baca M, Vivier E, Gasteiger G, Kuka M, Guidotti LG, Iannacone M. Fumagalli V, et al. Among authors: friedrich c. Sci Immunol. 2022 Feb 25;7(68):eabi6112. doi: 10.1126/sciimmunol.abi6112. Epub 2022 Feb 25. Sci Immunol. 2022. PMID: 35213210
In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors.
Zeis P, Lian M, Fan X, Herman JS, Hernandez DC, Gentek R, Elias S, Symowski C, Knöpper K, Peltokangas N, Friedrich C, Doucet-Ladeveze R, Kabat AM, Locksley RM, Voehringer D, Bajenoff M, Rudensky AY, Romagnani C, Grün D, Gasteiger G. Zeis P, et al. Among authors: friedrich c. Immunity. 2020 Oct 13;53(4):775-792.e9. doi: 10.1016/j.immuni.2020.09.002. Epub 2020 Sep 30. Immunity. 2020. PMID: 33002412 Free PMC article.
Divergent Role for STAT5 in the Adaptive Responses of Natural Killer Cells.
Wiedemann GM, Grassmann S, Lau CM, Rapp M, Villarino AV, Friedrich C, Gasteiger G, O'Shea JJ, Sun JC. Wiedemann GM, et al. Among authors: friedrich c. Cell Rep. 2020 Dec 15;33(11):108498. doi: 10.1016/j.celrep.2020.108498. Cell Rep. 2020. PMID: 33326784 Free PMC article.
Effector differentiation downstream of lineage commitment in ILC1s is driven by Hobit across tissues.
Friedrich C, Taggenbrock RLRE, Doucet-Ladevèze R, Golda G, Moenius R, Arampatzi P, Kragten NAM, Kreymborg K, Gomez de Agüero M, Kastenmüller W, Saliba AE, Grün D, van Gisbergen KPJM, Gasteiger G. Friedrich C, et al. Nat Immunol. 2021 Oct;22(10):1256-1267. doi: 10.1038/s41590-021-01013-0. Epub 2021 Aug 30. Nat Immunol. 2021. PMID: 34462601 Free PMC article.
Embryonic and neonatal waves generate distinct populations of hepatic ILC1s.
Sparano C, Solís-Sayago D, Vijaykumar A, Rickenbach C, Vermeer M, Ingelfinger F, Litscher G, Fonseca A, Mussak C, Mayoux M, Friedrich C, Nombela-Arrieta C, Gasteiger G, Becher B, Tugues S. Sparano C, et al. Among authors: friedrich c. Sci Immunol. 2022 Sep 2;7(75):eabo6641. doi: 10.1126/sciimmunol.abo6641. Epub 2022 Sep 2. Sci Immunol. 2022. PMID: 36054340
Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection.
Torcellan T, Friedrich C, Doucet-Ladevèze R, Ossner T, Solé VV, Riedmann S, Ugur M, Imdahl F, Rosshart SP, Arnold SJ, Gomez de Agüero M, Gagliani N, Flavell RA, Backes S, Kastenmüller W, Gasteiger G. Torcellan T, et al. Among authors: friedrich c. Immunity. 2024 Jan 9;57(1):124-140.e7. doi: 10.1016/j.immuni.2023.11.018. Epub 2023 Dec 28. Immunity. 2024. PMID: 38157853 Free PMC article.
Liver type 1 innate lymphoid cells undergo apoptosis in murine models of macrophage activation syndrome and are dispensable for disease.
De Visscher A, Vandeput M, Vandenhaute J, Malengier-Devlies B, Bernaerts E, Ahmadzadeh K, Filtjens J, Mitera T, Berghmans N, Van den Steen PE, Friedrich C, Gasteiger G, Wouters C, Matthys P. De Visscher A, et al. Among authors: friedrich c. Eur J Immunol. 2024 Dec;54(12):e2451043. doi: 10.1002/eji.202451043. Epub 2024 Sep 30. Eur J Immunol. 2024. PMID: 39348088
Autocrine TGF-β1 drives tissue-specific differentiation and function of resident NK cells.
Sparano C, Solís-Sayago D, Zangger NS, Rindlisbacher L, Van Hove H, Vermeer M, Westermann F, Mussak C, Rallo E, Dergun S, Litscher G, Xu Y, Bijnen M, Friedrich C, Greter M, Juranić Lisnić V, Becher B, Gasteiger G, Oxenius A, Tugues S. Sparano C, et al. Among authors: friedrich c. J Exp Med. 2025 Mar 3;222(3):e20240930. doi: 10.1084/jem.20240930. Epub 2024 Dec 18. J Exp Med. 2025. PMID: 39692745
747 results