Dunn JR - Search Results

1

Identification and Validation of Ikaros (IKZF1) as a Cancer Driver Gene for Marek's Disease Virus-Induced Lymphomas.

Steep A, Hildebrandt E, Xu H, Hearn C, Frishman D, Niikura M, Dunn JR, Kim T, Conrad SJ, Muir WM, Cheng HH. Steep A, et al. Among authors: dunn jr. Microorganisms. 2022 Feb 9;10(2):401. doi: 10.3390/microorganisms10020401. Microorganisms. 2022. PMID: 35208856 Free PMC article.

2

A MEQ-deleted Marek's disease virus cloned as a bacterial artificial chromosome is a highly efficacious vaccine.

Silva RF, Dunn JR, Cheng HH, Niikura M. Silva RF, et al. Among authors: dunn jr. Avian Dis. 2010 Jun;54(2):862-9. doi: 10.1637/9048-090409-Reg.1. Avian Dis. 2010. PMID: 20608531 Clinical Trial.

3

Characterizing the molecular basis of attenuation of Marek's disease virus via in vitro serial passage identifies de novo mutations in the helicase-primase subunit gene UL5 and other candidates associated with reduced virulence.

Hildebrandt E, Dunn JR, Perumbakkam S, Niikura M, Cheng HH. Hildebrandt E, et al. Among authors: dunn jr. J Virol. 2014 Jun;88(11):6232-42. doi: 10.1128/JVI.03869-13. Epub 2014 Mar 19. J Virol. 2014. PMID: 24648463 Free PMC article.

4

Characterizing in vivo stability and potential interactions of a UL5 helicase-primase mutation previously shown to reduce virulence and in vivo replication of Marek's disease virus.

Hildebrandt E, Dunn JR, Cheng HH. Hildebrandt E, et al. Among authors: dunn jr. Virus Res. 2015 May 4;203:1-3. doi: 10.1016/j.virusres.2015.03.011. Epub 2015 Mar 28. Virus Res. 2015. PMID: 25828576

5

Addition of a UL5 helicase-primase subunit point mutation eliminates bursal-thymic atrophy of Marek's disease virus ∆Meq recombinant virus but reduces vaccinal protection.

Hildebrandt E, Dunn JR, Cheng HH. Hildebrandt E, et al. Among authors: dunn jr. Avian Pathol. 2015;44(4):254-8. doi: 10.1080/03079457.2015.1041366. Avian Pathol. 2015. PMID: 25968878

6

The Mut UL5-I682R Marek's Disease Virus with a Single Nucleotide Mutation Within the Helicase-Primase Subunit Gene not only Reduces Virulence but also Provides Partial Vaccinal Protection Against Marek's Disease.

Hildebrandt E, Dunn JR, Cheng HH. Hildebrandt E, et al. Among authors: dunn jr. Avian Dis. 2015 Mar;59(1):94-7. doi: 10.1637/10929-090314-reg. Avian Dis. 2015. PMID: 26292541 Clinical Trial.

7

Fine mapping of QTL and genomic prediction using allele-specific expression SNPs demonstrates that the complex trait of genetic resistance to Marek's disease is predominantly determined by transcriptional regulation.

Cheng HH, Perumbakkam S, Pyrkosz AB, Dunn JR, Legarra A, Muir WM. Cheng HH, et al. Among authors: dunn jr. BMC Genomics. 2015 Oct 19;16:816. doi: 10.1186/s12864-015-2016-0. BMC Genomics. 2015. PMID: 26481588 Free PMC article.

8

Expression of Marek's Disease Virus Oncoprotein Meq During Infection in the Natural Host.

Tai SS, Hearn C, Umthong S, Agafitei O, Cheng HH, Dunn JR, Niikura M. Tai SS, et al. Among authors: dunn jr. Virology. 2017 Mar;503:103-113. doi: 10.1016/j.virol.2017.01.011. Epub 2017 Feb 1. Virology. 2017. PMID: 28160668 Free article.

9

Evaluation and Identification of Marek's Disease Virus BAC Clones as Standardized Reagents for Research.

Dunn JR, Reddy SM, Niikura M, Nair V, Fulton JE, Cheng HH. Dunn JR, et al. Avian Dis. 2017 Mar;61(1):107-114. doi: 10.1637/0005-2086-61.1.107. Avian Dis. 2017. PMID: 28301231

10

Attenuation of Marek's disease virus by codon pair deoptimization of a core gene.

Conrad SJ, Silva RF, Hearn CJ, Climans M, Dunn JR. Conrad SJ, et al. Among authors: dunn jr. Virology. 2018 Mar;516:219-226. doi: 10.1016/j.virol.2018.01.020. Virology. 2018. PMID: 29407380 Free article.

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