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Regulation of GTPase function by autophosphorylation.
Johnson CW, Seo HS, Terrell EM, Yang MH, KleinJan F, Gebregiworgis T, Gasmi-Seabrook GMC, Geffken EA, Lakhani J, Song K, Bashyal P, Popow O, Paulo JA, Liu A, Mattos C, Marshall CB, Ikura M, Morrison DK, Dhe-Paganon S, Haigis KM. Johnson CW, et al. Among authors: haigis km. Mol Cell. 2022 Mar 3;82(5):950-968.e14. doi: 10.1016/j.molcel.2022.02.011. Epub 2022 Feb 23. Mol Cell. 2022. PMID: 35202574 Free PMC article.
Tissue-Specific Oncogenic Activity of KRASA146T.
Poulin EJ, Bera AK, Lu J, Lin YJ, Strasser SD, Paulo JA, Huang TQ, Morales C, Yan W, Cook J, Nowak JA, Brubaker DK, Joughin BA, Johnson CW, DeStefanis RA, Ghazi PC, Gondi S, Wales TE, Iacob RE, Bogdanova L, Gierut JJ, Li Y, Engen JR, Perez-Mancera PA, Braun BS, Gygi SP, Lauffenburger DA, Westover KD, Haigis KM. Poulin EJ, et al. Among authors: haigis km. Cancer Discov. 2019 Jun;9(6):738-755. doi: 10.1158/2159-8290.CD-18-1220. Epub 2019 Apr 5. Cancer Discov. 2019. PMID: 30952657 Free PMC article.
High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down.
Li X, Pritykin Y, Concepcion CP, Lu Y, La Rocca G, Zhang M, King B, Cook PJ, Au YW, Popow O, Paulo JA, Otis HG, Mastroleo C, Ogrodowski P, Schreiner R, Haigis KM, Betel D, Leslie CS, Ventura A. Li X, et al. Among authors: haigis km. Mol Cell. 2020 Jul 2;79(1):167-179.e11. doi: 10.1016/j.molcel.2020.05.009. Epub 2020 Jun 3. Mol Cell. 2020. PMID: 32497496 Free PMC article.
Oncogenic K-Ras suppresses global miRNA function.
Shui B, Beyett TS, Chen Z, Li X, La Rocca G, Gazlay WM, Eck MJ, Lau KS, Ventura A, Haigis KM. Shui B, et al. Among authors: haigis km. Mol Cell. 2023 Jul 20;83(14):2509-2523.e13. doi: 10.1016/j.molcel.2023.06.008. Epub 2023 Jul 3. Mol Cell. 2023. PMID: 37402366 Free PMC article.
Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity.
Yang MH, Tran TH, Hunt B, Agnor R, Johnson CW, Shui B, Waybright TJ, Nowak JA, Stephen AG, Simanshu DK, Haigis KM. Yang MH, et al. Among authors: haigis km. Cancer Res. 2023 Oct 2;83(19):3176-3183. doi: 10.1158/0008-5472.CAN-22-3210. Cancer Res. 2023. PMID: 37556505 Free PMC article.
101 results