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Chemical Interrogation of Nuclear Size Identifies Compounds with Cancer Cell Line-Specific Effects on Migration and Invasion.
Tollis S, Rizzotto A, Pham NT, Koivukoski S, Sivakumar A, Shave S, Wildenhain J, Zuleger N, Keys JT, Culley J, Zheng Y, Lammerding J, Carragher NO, Brunton VG, Latonen L, Auer M, Tyers M, Schirmer EC. Tollis S, et al. Among authors: lammerding j. ACS Chem Biol. 2022 Mar 18;17(3):680-700. doi: 10.1021/acschembio.2c00004. Epub 2022 Feb 24. ACS Chem Biol. 2022. PMID: 35199530 Free PMC article.
Confinement hinders motility by inducing RhoA-mediated nuclear influx, volume expansion, and blebbing.
Mistriotis P, Wisniewski EO, Bera K, Keys J, Li Y, Tuntithavornwat S, Law RA, Perez-Gonzalez NA, Erdogmus E, Zhang Y, Zhao R, Sun SX, Kalab P, Lammerding J, Konstantopoulos K. Mistriotis P, et al. Among authors: lammerding j. J Cell Biol. 2019 Dec 2;218(12):4093-4111. doi: 10.1083/jcb.201902057. Epub 2019 Nov 5. J Cell Biol. 2019. PMID: 31690619 Free PMC article.
Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer.
Bell ES, Shah P, Zuela-Sopilniak N, Kim D, Varlet AA, Morival JLP, McGregor AL, Isermann P, Davidson PM, Elacqua JJ, Lakins JN, Vahdat L, Weaver VM, Smolka MB, Span PN, Lammerding J. Bell ES, et al. Among authors: lammerding j. Oncogene. 2022 Sep;41(36):4211-4230. doi: 10.1038/s41388-022-02420-9. Epub 2022 Jul 27. Oncogene. 2022. PMID: 35896617 Free PMC article.
Nuclear mechanics in cancer.
Denais C, Lammerding J. Denais C, et al. Among authors: lammerding j. Adv Exp Med Biol. 2014;773:435-70. doi: 10.1007/978-1-4899-8032-8_20. Adv Exp Med Biol. 2014. PMID: 24563360 Free PMC article. Review.
Non-muscle myosin IIB is critical for nuclear translocation during 3D invasion.
Thomas DG, Yenepalli A, Denais CM, Rape A, Beach JR, Wang YL, Schiemann WP, Baskaran H, Lammerding J, Egelhoff TT. Thomas DG, et al. Among authors: lammerding j. J Cell Biol. 2015 Aug 17;210(4):583-94. doi: 10.1083/jcb.201502039. Epub 2015 Aug 10. J Cell Biol. 2015. PMID: 26261182 Free PMC article.
124 results