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Chemical Interrogation of Nuclear Size Identifies Compounds with Cancer Cell Line-Specific Effects on Migration and Invasion.
Tollis S, Rizzotto A, Pham NT, Koivukoski S, Sivakumar A, Shave S, Wildenhain J, Zuleger N, Keys JT, Culley J, Zheng Y, Lammerding J, Carragher NO, Brunton VG, Latonen L, Auer M, Tyers M, Schirmer EC. Tollis S, et al. Among authors: carragher no. ACS Chem Biol. 2022 Mar 18;17(3):680-700. doi: 10.1021/acschembio.2c00004. Epub 2022 Feb 24. ACS Chem Biol. 2022. PMID: 35199530 Free PMC article.
Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53.
Timpson P, McGhee EJ, Morton JP, von Kriegsheim A, Schwarz JP, Karim SA, Doyle B, Quinn JA, Carragher NO, Edward M, Olson MF, Frame MC, Brunton VG, Sansom OJ, Anderson KI. Timpson P, et al. Among authors: carragher no. Cancer Res. 2011 Feb 1;71(3):747-57. doi: 10.1158/0008-5472.CAN-10-2267. Epub 2011 Jan 25. Cancer Res. 2011. PMID: 21266354 Free PMC article.
ADF and Cofilin1 Control Actin Stress Fibers, Nuclear Integrity, and Cell Survival.
Kanellos G, Zhou J, Patel H, Ridgway RA, Huels D, Gurniak CB, Sandilands E, Carragher NO, Sansom OJ, Witke W, Brunton VG, Frame MC. Kanellos G, et al. Among authors: carragher no. Cell Rep. 2015 Dec 1;13(9):1949-64. doi: 10.1016/j.celrep.2015.10.056. Epub 2015 Nov 19. Cell Rep. 2015. PMID: 26655907 Free PMC article.
Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase.
Fraser C, Dawson JC, Dowling R, Houston DR, Weiss JT, Munro AF, Muir M, Harrington L, Webster SP, Frame MC, Brunton VG, Patton EE, Carragher NO, Unciti-Broceta A. Fraser C, et al. Among authors: carragher no. J Med Chem. 2016 May 26;59(10):4697-710. doi: 10.1021/acs.jmedchem.6b00065. Epub 2016 May 4. J Med Chem. 2016. PMID: 27115835 Free PMC article.
126 results