Shen J - Search Results

1

VCSEL: PRIORITIZING SNP-SET BY PENALIZED VARIANCE COMPONENT SELECTION.

Kim J, Shen J, Wang A, Mehrotra DV, Ko S, Zhou JJ, Zhou H. Kim J, et al. Among authors: shen j. Ann Appl Stat. 2021 Dec;15(4):1652-1672. doi: 10.1214/21-aoas1491. Epub 2021 Dec 21. Ann Appl Stat. 2021. PMID: 35198092 Free PMC article.

2

Composite Kernel Association Test (CKAT) for SNP-set joint assessment of genotype and genotype-by-treatment interaction in Pharmacogenetics studies.

Zhang H, Zhao N, Mehrotra DV, Shen J. Zhang H, et al. Among authors: shen j. Bioinformatics. 2020 May 1;36(10):3162-3168. doi: 10.1093/bioinformatics/btaa125. Bioinformatics. 2020. PMID: 32101275

3

Genetic Association Reveals Protection against Recurrence of Clostridium difficile Infection with Bezlotoxumab Treatment.

Shen J, Mehrotra DV, Dorr MB, Zeng Z, Li J, Xu X, Nickle D, Holzinger ER, Chhibber A, Wilcox MH, Blanchard RL, Shaw PM. Shen J, et al. mSphere. 2020 May 6;5(3):e00232-20. doi: 10.1128/mSphere.00232-20. mSphere. 2020. PMID: 32376702 Free PMC article. Clinical Trial.

4

Multi-trait analysis of rare-variant association summary statistics using MTAR.

Luo L, Shen J, Zhang H, Chhibber A, Mehrotra DV, Tang ZZ. Luo L, et al. Among authors: shen j. Nat Commun. 2020 Jun 5;11(1):2850. doi: 10.1038/s41467-020-16591-0. Nat Commun. 2020. PMID: 32503972 Free PMC article.

5

CauchyCP: A powerful test under non-proportional hazards using Cauchy combination of change-point Cox regressions.

Zhang H, Li Q, Mehrotra DV, Shen J. Zhang H, et al. Among authors: shen j. Stat Methods Med Res. 2021 Nov;30(11):2447-2458. doi: 10.1177/09622802211037076. Epub 2021 Sep 14. Stat Methods Med Res. 2021. PMID: 34520293 Clinical Trial.

6

Germline HLA landscape does not predict efficacy of pembrolizumab monotherapy across solid tumor types.

Chhibber A, Huang L, Zhang H, Xu J, Cristescu R, Liu X, Mehrotra DV, Shen J, Shaw PM, Hellmann MD, Snyder A. Chhibber A, et al. Among authors: shen j. Immunity. 2022 Jan 11;55(1):56-64.e4. doi: 10.1016/j.immuni.2021.12.006. Epub 2022 Jan 5. Immunity. 2022. PMID: 34986342 Free article.

7

GWAS of longitudinal trajectories at biobank scale.

Ko S, German CA, Jensen A, Shen J, Wang A, Mehrotra DV, Sun YV, Sinsheimer JS, Zhou H, Zhou JJ. Ko S, et al. Among authors: shen j. Am J Hum Genet. 2022 Mar 3;109(3):433-445. doi: 10.1016/j.ajhg.2022.01.018. Epub 2022 Feb 22. Am J Hum Genet. 2022. PMID: 35196515 Free PMC article.

8

A statistical perspective on baseline adjustment in pharmacogenomic genome-wide association studies of quantitative change.

Zhang H, Chhibber A, Shaw PM, Mehrotra DV, Shen J. Zhang H, et al. Among authors: shen j. NPJ Genom Med. 2022 Jun 9;7(1):33. doi: 10.1038/s41525-022-00303-2. NPJ Genom Med. 2022. PMID: 35680959 Free PMC article.

9

Pharmacogenomics polygenic risk score for drug response prediction using PRS-PGx methods.

Zhai S, Zhang H, Mehrotra DV, Shen J. Zhai S, et al. Among authors: shen j. Nat Commun. 2022 Sep 8;13(1):5278. doi: 10.1038/s41467-022-32407-9. Nat Commun. 2022. PMID: 36075892 Free PMC article. Clinical Trial.

10

A fast and powerful linear mixed model approach for genotype-environment interaction tests in large-scale GWAS.

Zhong W, Chhibber A, Luo L, Mehrotra DV, Shen J. Zhong W, et al. Among authors: shen j. Brief Bioinform. 2023 Jan 19;24(1):bbac547. doi: 10.1093/bib/bbac547. Brief Bioinform. 2023. PMID: 36545787

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