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Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics.
Zhang AMY, Chu KH, Daly BF, Ruiter T, Dou Y, Yang JCC, de Winter TJJ, Chhuor J, Wang S, Flibotte S, Zhao YB, Hu X, Li H, Rideout EJ, Schaeffer DF, Johnson JD, Kopp JL. Zhang AMY, et al. Among authors: kopp jl. Cancer Metab. 2022 Feb 21;10(1):5. doi: 10.1186/s40170-022-00282-z. Cancer Metab. 2022. PMID: 35189981 Free PMC article.
Endogenous Hyperinsulinemia Contributes to Pancreatic Cancer Development.
Zhang AMY, Magrill J, de Winter TJJ, Hu X, Skovsø S, Schaeffer DF, Kopp JL, Johnson JD. Zhang AMY, et al. Among authors: kopp jl. Cell Metab. 2019 Sep 3;30(3):403-404. doi: 10.1016/j.cmet.2019.07.003. Epub 2019 Aug 1. Cell Metab. 2019. PMID: 31378465 Free article. No abstract available.
Hyperinsulinemia in Obesity, Inflammation, and Cancer.
Zhang AMY, Wellberg EA, Kopp JL, Johnson JD. Zhang AMY, et al. Among authors: kopp jl. Diabetes Metab J. 2021 May;45(3):285-311. doi: 10.4093/dmj.2020.0250. Epub 2021 Mar 29. Diabetes Metab J. 2021. PMID: 33775061 Free PMC article. Review.
Hyperinsulinemia in Obesity, Inflammation, and Cancer.
Zhang AMY, Wellberg EA, Kopp JL, Johnson JD. Zhang AMY, et al. Among authors: kopp jl. Diabetes Metab J. 2021 Jul;45(4):622. doi: 10.4093/dmj.2021.0131. Epub 2021 Jul 30. Diabetes Metab J. 2021. PMID: 34352994 Free PMC article. No abstract available.
Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin.
Espinet E, Gu Z, Imbusch CD, Giese NA, Büscher M, Safavi M, Weisenburger S, Klein C, Vogel V, Falcone M, Insua-Rodríguez J, Reitberger M, Thiel V, Kossi SO, Muckenhuber A, Sarai K, Lee AYL, Backx E, Zarei S, Gaida MM, Rodríguez-Paredes M, Donato E, Yen HY, Eils R, Schlesner M, Pfarr N, Hackert T, Plass C, Brors B, Steiger K, Weichenhan D, Arda HE, Rooman I, Kopp JL, Strobel O, Weichert W, Sprick MR, Trumpp A. Espinet E, et al. Among authors: kopp jl. Cancer Discov. 2021 Mar;11(3):638-659. doi: 10.1158/2159-8290.CD-20-1202. Epub 2020 Oct 15. Cancer Discov. 2021. PMID: 33060108 Free PMC article.
Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice.
Erener S, Ellis CE, Ramzy A, Glavas MM, O'Dwyer S, Pereira S, Wang T, Pang J, Bruin JE, Riedel MJ, Baker RK, Webber TD, Lesina M, Blüher M, Algül H, Kopp JL, Herzig S, Kieffer TJ. Erener S, et al. Among authors: kopp jl. Cell Rep Med. 2021 Nov 11;2(11):100434. doi: 10.1016/j.xcrm.2021.100434. eCollection 2021 Nov 16. Cell Rep Med. 2021. PMID: 34841287 Free PMC article.
43 results