Supuran CT - Search Results

1

Discovery of new carbonic anhydrase IX inhibitors as anticancer agents by toning the hydrophobic and hydrophilic rims of the active site to encounter the dual-tail approach.

Tawfik HO, Petreni A, Supuran CT, El-Hamamsy MH. Tawfik HO, et al. Among authors: supuran ct. Eur J Med Chem. 2022 Mar 15;232:114190. doi: 10.1016/j.ejmech.2022.114190. Epub 2022 Feb 12. Eur J Med Chem. 2022. PMID: 35182815

2

Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring?

Scozzafava A, Menabuoni L, Mincione F, Briganti F, Mincione G, Supuran CT. Scozzafava A, et al. Among authors: supuran ct. J Med Chem. 1999 Jul 15;42(14):2641-50. doi: 10.1021/jm9900523. J Med Chem. 1999. PMID: 10411484

3

Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route.

Scozzafava A, Briganti F, Mincione G, Menabuoni L, Mincione F, Supuran CT. Scozzafava A, et al. Among authors: supuran ct. J Med Chem. 1999 Sep 9;42(18):3690-700. doi: 10.1021/jm9901879. J Med Chem. 1999. PMID: 10479300

4

Carbonic anhydrase inhibitors: synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes.

Scozzafava A, Briganti F, Ilies MA, Supuran CT. Scozzafava A, et al. Among authors: supuran ct. J Med Chem. 2000 Jan 27;43(2):292-300. doi: 10.1021/jm990479+. J Med Chem. 2000. PMID: 10649985

5

Carbonic anhydrase inhibitors: topical sulfonamide antiglaucoma agents incorporating secondary amine moieties.

Renzi G, Scozzafava A, Supuran CT. Renzi G, et al. Among authors: supuran ct. Bioorg Med Chem Lett. 2000 Apr 3;10(7):673-6. doi: 10.1016/s0960-894x(00)00075-5. Bioorg Med Chem Lett. 2000. PMID: 10762051

6

Carbonic anhydrase inhibitors - part 78(#). Synthesis of water-soluble sulfonamides incorporating beta-alanyl moieties, possessing long lasting-intraocular pressure lowering properties via the topical route.

Supuran CT, Briganti F, Menabuoni L, Mincione G, Mincione F, Scozzafava A. Supuran CT, et al. Eur J Med Chem. 2000 Mar;35(3):309-21. doi: 10.1016/s0223-5234(00)00130-6. Eur J Med Chem. 2000. PMID: 10785557

7

Carbonic anhydrase inhibitors: synthesis of N-morpholylthiocarbonylsulfenylamino aromatic/heterocyclic sulfonamides and their interaction with isozymes I, II and IV.

Scozzafava A, Supuran CT. Scozzafava A, et al. Among authors: supuran ct. Bioorg Med Chem Lett. 2000 May 15;10(10):1117-20. doi: 10.1016/s0960-894x(00)00178-5. Bioorg Med Chem Lett. 2000. PMID: 10843231

8

Carbonic anhydrase inhibitors: sulfonamides incorporating furan-, thiophene- and pyrrole-carboxamido groups possess strong topical intraocular pressure lowering properties as aqueous suspensions.

Ilies M, Supuran CT, Scozzafava A, Casini A, Mincione F, Menabuoni L, Caproiu MT, Maganu M, Banciu MD. Ilies M, et al. Among authors: supuran ct. Bioorg Med Chem. 2000 Aug;8(8):2145-55. doi: 10.1016/s0968-0896(00)00143-7. Bioorg Med Chem. 2000. PMID: 11003159

9

Carbonic anhydrase inhibitors. Part 86. A QSAR study on some sulfonamide drugs which lower intra-ocular pressure, using the ACE non-linear statistical method.

Clare BW, Supuran CT. Clare BW, et al. Among authors: supuran ct. Eur J Med Chem. 2000 Sep;35(9):859-65. doi: 10.1016/s0223-5234(00)00182-3. Eur J Med Chem. 2000. PMID: 11006487

10

Carbonic anhydrase and matrix metalloproteinase inhibitors: sulfonylated amino acid hydroxamates with MMP inhibitory properties act as efficient inhibitors of CA isozymes I, II, and IV, and N-hydroxysulfonamides inhibit both these zinc enzymes.

Scozzafava A, Supuran CT. Scozzafava A, et al. Among authors: supuran ct. J Med Chem. 2000 Oct 5;43(20):3677-87. doi: 10.1021/jm000027t. J Med Chem. 2000. PMID: 11020282

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