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Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists.
Wu M, Carballo-Jane E, Zhou H, Zafian P, Dai G, Liu M, Lao J, Kelly T, Shao D, Gorski J, Pissarnitski D, Kekec A, Chen Y, Previs SF, Scapin G, Gomez-Llorente Y, Hollingsworth SA, Yan L, Feng D, Huo P, Walford G, Erion MD, Kelley DE, Lin S, Mu J. Wu M, et al. Among authors: previs sf. Nat Commun. 2022 Feb 17;13(1):942. doi: 10.1038/s41467-022-28561-9. Nat Commun. 2022. PMID: 35177603 Free PMC article.
Glucagon receptor antagonism induces increased cholesterol absorption.
Guan HP, Yang X, Lu K, Wang SP, Castro-Perez JM, Previs S, Wright M, Shah V, Herath K, Xie D, Szeto D, Forrest G, Xiao JC, Palyha O, Sun LP, Andryuk PJ, Engel SS, Xiong Y, Lin S, Kelley DE, Erion MD, Davis HR, Wang L. Guan HP, et al. J Lipid Res. 2015 Nov;56(11):2183-95. doi: 10.1194/jlr.M060897. Epub 2015 Sep 15. J Lipid Res. 2015. PMID: 26373568 Free PMC article.
Quantifying rates of glucose production in vivo following an intraperitoneal tracer bolus.
Wang SP, Zhou D, Yao Z, Satapati S, Chen Y, Daurio NA, Petrov A, Shen X, Metzger D, Yin W, Nawrocki AR, Eiermann GJ, Hwa J, Fancourt C, Miller C, Herath K, Roddy TP, Slipetz D, Erion MD, Previs SF, Kelley DE. Wang SP, et al. Among authors: previs sf. Am J Physiol Endocrinol Metab. 2016 Dec 1;311(6):E911-E921. doi: 10.1152/ajpendo.00182.2016. Epub 2016 Sep 20. Am J Physiol Endocrinol Metab. 2016. PMID: 27651111 Free article.
The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys.
Singh SB, Kang L, Nawrocki AR, Zhou D, Wu M, Previs S, Miller C, Liu H, Hines CD, Madeira M, Cao J, Herath K, Spears LD, Semenkovich CF, Wang L, Kelley DE, Li C, Guan HP. Singh SB, et al. PLoS One. 2016 Oct 3;11(10):e0164133. doi: 10.1371/journal.pone.0164133. eCollection 2016. PLoS One. 2016. PMID: 27695056 Free PMC article.
Phenotyping of adipose, liver, and skeletal muscle insulin resistance and response to pioglitazone in spontaneously obese rhesus monkeys.
Shang J, Previs SF, Conarello S, Chng K, Zhu Y, Souza SC, Staup M, Chen Y, Xie D, Zycband E, Schlessinger K, Johnson VP, Arreaza G, Liu F, Levitan D, Wang L, van Heek M, Erion M, Wang Y, Kelley DE. Shang J, et al. Among authors: previs sf. Am J Physiol Endocrinol Metab. 2017 Apr 1;312(4):E235-E243. doi: 10.1152/ajpendo.00398.2016. Epub 2017 Jan 31. Am J Physiol Endocrinol Metab. 2017. PMID: 28143858 Free article.
152 results