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Page 1
Incorporating protein precipitation to resolve hybrid IP-LC-MS assay interference for ultrasensitive quantification of intact therapeutic insulin dimer in human plasma.
Sun L, Xu Y, Dube N, Anderson M, Breidinger S, Vaddady P, Thornton B, Morrow L, Matthews RP, Stoch SA, Woolf EJ. Sun L, et al. Among authors: thornton b. J Pharm Biomed Anal. 2022 Apr 1;212:114639. doi: 10.1016/j.jpba.2022.114639. Epub 2022 Feb 2. J Pharm Biomed Anal. 2022. PMID: 35176654
Clinical Evaluation of MK-2640: An Insulin Analog With Glucose-Responsive Properties.
Krug AW, Visser SAG, Tsai K, Kandala B, Fancourt C, Thornton B, Morrow L, Kaarsholm NC, Bernstein HS, Stoch SA, Crutchlow M, Kelley DE, Iwamoto M. Krug AW, et al. Among authors: thornton b. Clin Pharmacol Ther. 2019 Feb;105(2):417-425. doi: 10.1002/cpt.1215. Epub 2018 Sep 30. Clin Pharmacol Ther. 2019. PMID: 30125349 Clinical Trial.
Validation of a microdose probe drug cocktail for clinical drug interaction assessments for drug transporters and CYP3A.
Prueksaritanont T, Tatosian DA, Chu X, Railkar R, Evers R, Chavez-Eng C, Lutz R, Zeng W, Yabut J, Chan GH, Cai X, Latham AH, Hehman J, Stypinski D, Brejda J, Zhou C, Thornton B, Bateman KP, Fraser I, Stoch SA. Prueksaritanont T, et al. Among authors: thornton b. Clin Pharmacol Ther. 2017 Apr;101(4):519-530. doi: 10.1002/cpt.525. Epub 2016 Dec 10. Clin Pharmacol Ther. 2017. PMID: 27943276 Clinical Trial.
Population PK Analyses of Ubrogepant (MK-1602), a CGRP Receptor Antagonist: Enriching In-Clinic Plasma PK Sampling With Outpatient Dried Blood Spot Sampling.
Li CC, Dockendorf M, Kowalski K, Yang B, Xu Y, Xie I, Kleijn HJ, Bosch R, Jones C, Thornton B, Marcantonio EE, Voss T, Bateman KP, Kothare PA. Li CC, et al. Among authors: thornton b. J Clin Pharmacol. 2018 Mar;58(3):294-303. doi: 10.1002/jcph.1021. Epub 2017 Nov 14. J Clin Pharmacol. 2018. PMID: 29136283 Clinical Trial.
An Exploratory Study Using Electronic Medical Records to Assess the Feasibility of Establishing Cohorts of Patients with Genetic Causes of Parkinson's Disease.
Lee SJ, Shaw PM, Thornton B, Kumar A, Eizik M, Goldstaub D, Braun T, Teper G, Pai JK, Chodick G, Bienfait K, Levitan D, Beller D, Chris Min K, Jonathan D, Voss T, Fox CS, Aubrey Stoch S, Struyk AF, Vainstein G. Lee SJ, et al. Among authors: thornton b. J Parkinsons Dis. 2022;12(5):1645-1653. doi: 10.3233/JPD-212703. J Parkinsons Dis. 2022. PMID: 35466950 Free PMC article.
Rhinovirus-16 induced temporal interferon responses in nasal epithelium links with viral clearance and symptoms.
Ravi A, Chang M, van de Pol M, Yang S, Aliprantis A, Thornton B, Carayannopoulos LN, Bautmans A, Robberechts M, De Lepeleire I, Singh D, Hohlfeld JM, Sterk PJ, Krug N, Lutter R; U-BIOPRED Study Group. Ravi A, et al. Among authors: thornton b. Clin Exp Allergy. 2019 Dec;49(12):1587-1597. doi: 10.1111/cea.13481. Epub 2019 Oct 31. Clin Exp Allergy. 2019. PMID: 31400236 Free PMC article. Clinical Trial.
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics.
Lefaudeux D, De Meulder B, Loza MJ, Peffer N, Rowe A, Baribaud F, Bansal AT, Lutter R, Sousa AR, Corfield J, Pandis I, Bakke PS, Caruso M, Chanez P, Dahlén SE, Fleming LJ, Fowler SJ, Horvath I, Krug N, Montuschi P, Sanak M, Sandstrom T, Shaw DE, Singer F, Sterk PJ, Roberts G, Adcock IM, Djukanovic R, Auffray C, Chung KF; U-BIOPRED Study Group. Lefaudeux D, et al. J Allergy Clin Immunol. 2017 Jun;139(6):1797-1807. doi: 10.1016/j.jaci.2016.08.048. Epub 2016 Oct 20. J Allergy Clin Immunol. 2017. PMID: 27773852 Free article.
Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study.
Loza MJ, Djukanovic R, Chung KF, Horowitz D, Ma K, Branigan P, Barnathan ES, Susulic VS, Silkoff PE, Sterk PJ, Baribaud F; ADEPT (Airways Disease Endotyping for Personalized Therapeutics) and U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome Consortium) investigators. Loza MJ, et al. Respir Res. 2016 Dec 15;17(1):165. doi: 10.1186/s12931-016-0482-9. Respir Res. 2016. PMID: 27978840 Free PMC article.
Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study.
Kolmert J, Gómez C, Balgoma D, Sjödin M, Bood J, Konradsen JR, Ericsson M, Thörngren JO, James A, Mikus M, Sousa AR, Riley JH, Bates S, Bakke PS, Pandis I, Caruso M, Chanez P, Fowler SJ, Geiser T, Howarth P, Horváth I, Krug N, Montuschi P, Sanak M, Behndig A, Shaw DE, Knowles RG, Holweg CTJ, Wheelock ÅM, Dahlén B, Nordlund B, Alving K, Hedlin G, Chung KF, Adcock IM, Sterk PJ, Djukanovic R, Dahlén SE, Wheelock CE; U-BIOPRED Study Group, on behalf of the U-BIOPRED Study Group. Kolmert J, et al. Am J Respir Crit Care Med. 2021 Jan 1;203(1):37-53. doi: 10.1164/rccm.201909-1869OC. Am J Respir Crit Care Med. 2021. PMID: 32667261 Free PMC article.
214 results