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Pancreatic islet beta cell-specific deletion of G6pc2 reduces fasting blood glucose.
Bosma KJ, Rahim M, Singh K, Goleva SB, Wall ML, Xia J, Syring KE, Oeser JK, Poffenberger G, McGuinness OP, Means AL, Powers AC, Li WH, Davis LK, Young JD, O'Brien RM. Bosma KJ, et al. J Mol Endocrinol. 2020 May;64(4):235-248. doi: 10.1530/JME-20-0031. J Mol Endocrinol. 2020. PMID: 32213654 Free PMC article.
Potential positive and negative consequences of ZnT8 inhibition.
Syring KE, Bosma KJ, Goleva SB, Singh K, Oeser JK, Lopez CA, Skaar EP, McGuinness OP, Davis LK, Powell DR, O'Brien RM. Syring KE, et al. Among authors: bosma kj. J Endocrinol. 2020 Aug;246(2):189-205. doi: 10.1530/JOE-20-0138. J Endocrinol. 2020. PMID: 32485672 Free PMC article.
Pharmacological blockade of the EP3 prostaglandin E2 receptor in the setting of type 2 diabetes enhances β-cell proliferation and identity and relieves oxidative damage.
Bosma KJ, Andrei SR, Katz LS, Smith AA, Dunn JC, Ricciardi VF, Ramirez MA, Baumel-Alterzon S, Pace WA, Carroll DT, Overway EM, Wolf EM, Kimple ME, Sheng Q, Scott DK, Breyer RM, Gannon M. Bosma KJ, et al. Mol Metab. 2021 Dec;54:101347. doi: 10.1016/j.molmet.2021.101347. Epub 2021 Oct 6. Mol Metab. 2021. PMID: 34626853 Free PMC article.
Macrophages and neutrophils are necessary for ER stress-induced β cell loss.
Yang B, Yang L, Wang Y, Maddison LA, Tang Z, Haigh S, Gong Y, Zhang Y, Covington BA, Bosma KJ, Tong X, Page-McCaw P, Gannon M, Deng Q, Chen W. Yang B, et al. Among authors: bosma kj. Cell Rep. 2022 Aug 23;40(8):111255. doi: 10.1016/j.celrep.2022.111255. Cell Rep. 2022. PMID: 36001973 Free PMC article.
40 results