Goncheva MI - Search Results

1

Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production.

Tuffs SW, Goncheva MI, Xu SX, Craig HC, Kasper KJ, Choi J, Flannagan RS, Kerfoot SM, Heinrichs DE, McCormick JK. Tuffs SW, et al. Among authors: goncheva mi. Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2115987119. doi: 10.1073/pnas.2115987119. Proc Natl Acad Sci U S A. 2022. PMID: 35165181 Free PMC article.

2

The Staphylococcus aureus superantigen SElX is a bifunctional toxin that inhibits neutrophil function.

Tuffs SW, James DBA, Bestebroer J, Richards AC, Goncheva MI, O'Shea M, Wee BA, Seo KS, Schlievert PM, Lengeling A, van Strijp JA, Torres VJ, Fitzgerald JR. Tuffs SW, et al. Among authors: goncheva mi. PLoS Pathog. 2017 Sep 7;13(9):e1006461. doi: 10.1371/journal.ppat.1006461. eCollection 2017 Sep. PLoS Pathog. 2017. PMID: 28880920 Free PMC article.

3

Staphylococcus pseudintermedius Surface Protein L (SpsL) Is Required for Abscess Formation in a Murine Model of Cutaneous Infection.

Richards AC, O'Shea M, Beard PM, Goncheva MI, Tuffs SW, Fitzgerald JR, Lengeling A. Richards AC, et al. Among authors: goncheva mi. Infect Immun. 2018 Oct 25;86(11):e00631-18. doi: 10.1128/IAI.00631-18. Print 2018 Nov. Infect Immun. 2018. PMID: 30181348 Free PMC article.

4

Stress-induced inactivation of the Staphylococcus aureus purine biosynthesis repressor leads to hypervirulence.

Goncheva MI, Flannagan RS, Sterling BE, Laakso HA, Friedrich NC, Kaiser JC, Watson DW, Wilson CH, Sheldon JR, McGavin MJ, Kiser PK, Heinrichs DE. Goncheva MI, et al. Nat Commun. 2019 Feb 15;10(1):775. doi: 10.1038/s41467-019-08724-x. Nat Commun. 2019. PMID: 30770821 Free PMC article.

5

De Novo Purine Biosynthesis Is Required for Intracellular Growth of Staphylococcus aureus and for the Hypervirulence Phenotype of a purR Mutant.

Goncheva MI, Flannagan RS, Heinrichs DE. Goncheva MI, et al. Infect Immun. 2020 Apr 20;88(5):e00104-20. doi: 10.1128/IAI.00104-20. Print 2020 Apr 20. Infect Immun. 2020. PMID: 32094249 Free PMC article.

6

Staphylococcus aureus Lipase 1 Enhances Influenza A Virus Replication.

Goncheva MI, Conceicao C, Tuffs SW, Lee HM, Quigg-Nicol M, Bennet I, Sargison F, Pickering AC, Hussain S, Gill AC, Dutia BM, Digard P, Fitzgerald JR. Goncheva MI, et al. mBio. 2020 Jul 7;11(4):e00975-20. doi: 10.1128/mBio.00975-20. mBio. 2020. PMID: 32636247 Free PMC article.

7

Coagulase-negative staphylococci release a purine analog that inhibits Staphylococcus aureus virulence.

Chin D, Goncheva MI, Flannagan RS, Deecker SR, Guariglia-Oropeza V, Ensminger AW, Heinrichs DE. Chin D, et al. Among authors: goncheva mi. Nat Commun. 2021 Mar 25;12(1):1887. doi: 10.1038/s41467-021-22175-3. Nat Commun. 2021. PMID: 33767207 Free PMC article.

8

Mutations in a Membrane Permease or hpt Lead to 6-Thioguanine Resistance in Staphylococcus aureus.

Chin D, Goncheva MI, Flannagan RS, Heinrichs DE. Chin D, et al. Among authors: goncheva mi. Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0076021. doi: 10.1128/AAC.00760-21. Epub 2021 Aug 17. Antimicrob Agents Chemother. 2021. PMID: 34125595 Free PMC article.

9

Nucleotide biosynthesis: the base of bacterial pathogenesis.

Goncheva MI, Chin D, Heinrichs DE. Goncheva MI, et al. Trends Microbiol. 2022 Aug;30(8):793-804. doi: 10.1016/j.tim.2021.12.007. Epub 2022 Jan 22. Trends Microbiol. 2022. PMID: 35074276 Review.

10

MRSA Isolates from Patients with Persistent Bacteremia Generate Nonstable Small Colony Variants In Vitro within Macrophages and Endothelial Cells during Prolonged Vancomycin Exposure.

Fauerharmel-Nunes T, Flannagan RS, Goncheva MI, Bayer AS, Fowler VG Jr, Chan LC, Yeaman MR, Xiong YQ, Heinrichs DE. Fauerharmel-Nunes T, et al. Among authors: goncheva mi. Infect Immun. 2023 Jan 24;91(1):e0042322. doi: 10.1128/iai.00423-22. Epub 2023 Jan 5. Infect Immun. 2023. PMID: 36602380 Free PMC article.

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