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Page 1
Dysregulated PI3K Signaling in B Cells of CVID Patients.
Harder I, Münchhalfen M, Andrieux G, Boerries M, Grimbacher B, Eibel H, Maccari ME, Ehl S, Wienands J, Jellusova J, Warnatz K, Keller B. Harder I, et al. Cells. 2022 Jan 28;11(3):464. doi: 10.3390/cells11030464. Cells. 2022. PMID: 35159274 Free PMC article.
Impaired polysaccharide responsiveness without agammaglobulinaemia in three patients with hypomorphic mutations in Bruton Tyrosine Kinase-No detection by newborn screening for primary immunodeficiencies.
Krüger R, Baumann U, Borte S, Kölsch U, Lorenz MR, Keller B, Harder I, Warnatz K, Ehl S, Schwarz K, Wahn V, von Bernuth H. Krüger R, et al. Among authors: harder i. Scand J Immunol. 2020 Jan;91(1):e12811. doi: 10.1111/sji.12811. Epub 2019 Oct 30. Scand J Immunol. 2020. PMID: 31378960 Free article.
The Antigen Presenting Potential of CD21low B Cells.
Reincke ME, Payne KJ, Harder I, Strohmeier V, Voll RE, Warnatz K, Keller B. Reincke ME, et al. Among authors: harder i. Front Immunol. 2020 Oct 21;11:535784. doi: 10.3389/fimmu.2020.535784. eCollection 2020. Front Immunol. 2020. PMID: 33193306 Free PMC article. Clinical Trial.
The expansion of human T-bethighCD21low B cells is T cell dependent.
Keller B, Strohmeier V, Harder I, Unger S, Payne KJ, Andrieux G, Boerries M, Felixberger PT, Landry JJM, Nieters A, Rensing-Ehl A, Salzer U, Frede N, Usadel S, Elling R, Speckmann C, Hainmann I, Ralph E, Gilmour K, Wentink MWJ, van der Burg M, Kuehn HS, Rosenzweig SD, Kölsch U, von Bernuth H, Kaiser-Labusch P, Gothe F, Hambleton S, Vlagea AD, Garcia Garcia A, Alsina L, Markelj G, Avcin T, Vasconcelos J, Guedes M, Ding JY, Ku CL, Shadur B, Avery DT, Venhoff N, Thiel J, Becker H, Erazo-Borrás L, Trujillo-Vargas CM, Franco JL, Fieschi C, Okada S, Gray PE, Uzel G, Casanova JL, Fliegauf M, Grimbacher B, Eibel H, Ehl S, Voll RE, Rizzi M, Stepensky P, Benes V, Ma CS, Bossen C, Tangye SG, Warnatz K. Keller B, et al. Among authors: harder i. Sci Immunol. 2021 Oct 15;6(64):eabh0891. doi: 10.1126/sciimmunol.abh0891. Epub 2021 Oct 8. Sci Immunol. 2021. PMID: 34623902
Interferon-Driven Immune Dysregulation in Common Variable Immunodeficiency-Associated Villous Atrophy and Norovirus Infection.
Strohmeier V, Andrieux G, Unger S, Pascual-Reguant A, Klocperk A, Seidl M, Marques OC, Eckert M, Gräwe K, Shabani M, von Spee-Mayer C, Friedmann D, Harder I, Gutenberger S, Keller B, Proietti M, Bulashevska A, Grimbacher B, Provaznik J, Benes V, Goldacker S, Schell C, Hauser AE, Boerries M, Hasselblatt P, Warnatz K. Strohmeier V, et al. Among authors: harder i. J Clin Immunol. 2023 Feb;43(2):371-390. doi: 10.1007/s10875-022-01379-2. Epub 2022 Oct 25. J Clin Immunol. 2023. PMID: 36282455 Free PMC article.
Type 2 Immune-Dominant Endotype Is Not Associated With Increased Responsiveness to Dupilumab Treatment in Adult Atopic Dermatitis Patients.
Dekkers C, Smits H, Stölzl D, Spekhorst L, Knol E, van Wijk F, Harder I, Werfel T, Schmitt J, Kleinheinz A, Abraham S, Thijs J, Weidinger S, de Bruin-Weller M, Bakker D, Drylewicz J. Dekkers C, et al. Among authors: harder i. Clin Exp Allergy. 2024 Oct 24. doi: 10.1111/cea.14585. Online ahead of print. Clin Exp Allergy. 2024. PMID: 39449187 No abstract available.
Clinical and molecular response to dupilumab treatment in pediatric atopic dermatitis: Results of the German TREATkids registry.
Stölzl D, Sander N, Siegels D, Harder I, Kind B, Fonfara M, Heinrich L, Ott H, Abraham S, Neustädter I, Kleinheinz A, Gerdes S, Wollenberg A, Lau S, Nemat K, Heratizadeh A, Gellhaus I, Werfel T, Schmitt J, Weidinger S; TREATgermany study group. Stölzl D, et al. Among authors: harder i. Allergy. 2024 Oct;79(10):2849-2852. doi: 10.1111/all.16147. Epub 2024 May 7. Allergy. 2024. PMID: 38712730 No abstract available.
Obesity is linked to disease severity in moderate to severe atopic dermatitis-Data from the prospective observational TREATgermany registry.
Traidl S, Hollstein MM, Kroeger N, Fischer S, Heratizadeh A, Heinrich L, Kind B, Siegels D, Abraham S, Schäfer T, Augustin M, Harder I, Pinter A, Schäkel K, Wollenberg A, Ertner K, Ramaker-Brunke J, Bong A, Quist S, Gorriahn-Maiterth H, Schenck F, Sticherling M, Effendy I, Schwarz B, Handrick C, Asmussen A, Weidinger S, Schmitt J, Werfel T; TREATgermany Study Group. Traidl S, et al. Among authors: harder i. J Eur Acad Dermatol Venereol. 2025 Jan;39(1):136-144. doi: 10.1111/jdv.20042. Epub 2024 Apr 25. J Eur Acad Dermatol Venereol. 2025. PMID: 38661511 Free PMC article.
89 results