Qi W - Search Results

1

The binding mechanism of NHWD-870 to bromodomain-containing protein 4 based on molecular dynamics simulations and free energy calculation.

Shi M, He J, Weng T, Shi N, Qi W, Guo Y, Chen T, Chen L, Xu D. Shi M, et al. Among authors: qi w. Phys Chem Chem Phys. 2022 Feb 23;24(8):5125-5137. doi: 10.1039/d1cp05490b. Phys Chem Chem Phys. 2022. PMID: 35156677

2

N-(Pyrimidin-2-yl)-1,2,3,4-tetrahydroisoquinolin-6-amine Derivatives as Selective Janus Kinase 2 Inhibitors for the Treatment of Myeloproliferative Neoplasms.

Yang T, Hu M, Chen Y, Xiang M, Tang M, Qi W, Shi M, He J, Yuan X, Zhang C, Liu K, Li J, Yang Z, Chen L. Yang T, et al. Among authors: qi w. J Med Chem. 2020 Dec 10;63(23):14921-14936. doi: 10.1021/acs.jmedchem.0c01488. Epub 2020 Nov 30. J Med Chem. 2020. PMID: 33256400

3

Identification and optimization of piperine analogues as neuroprotective agents for the treatment of Parkinson's disease via the activation of Nrf2/keap1 pathway.

Wang L, Cai X, Shi M, Xue L, Kuang S, Xu R, Qi W, Li Y, Ma X, Zhang R, Hong F, Ye H, Chen L. Wang L, et al. Among authors: qi w. Eur J Med Chem. 2020 Aug 1;199:112385. doi: 10.1016/j.ejmech.2020.112385. Epub 2020 May 5. Eur J Med Chem. 2020. PMID: 32402936

4

Identification of a Novel 2,8-Diazaspiro[4.5]decan-1-one Derivative as a Potent and Selective Dual TYK2/JAK1 Inhibitor for the Treatment of Inflammatory Bowel Disease.

Yang T, Cui X, Tang M, Qi W, Zhu Z, Shi M, Yang L, Pei H, Zhang W, Xie L, Xu Y, Yang Z, Chen L. Yang T, et al. Among authors: qi w. J Med Chem. 2022 Feb 24;65(4):3151-3172. doi: 10.1021/acs.jmedchem.1c01137. Epub 2022 Feb 3. J Med Chem. 2022. PMID: 35113547

5

Discovery of Potent and Orally Effective Dual Janus Kinase 2/FLT3 Inhibitors for the Treatment of Acute Myelogenous Leukemia and Myeloproliferative Neoplasms.

Yang T, Hu M, Qi W, Yang Z, Tang M, He J, Chen Y, Bai P, Yuan X, Zhang C, Liu K, Lu Y, Xiang M, Chen L. Yang T, et al. Among authors: qi w. J Med Chem. 2019 Nov 27;62(22):10305-10320. doi: 10.1021/acs.jmedchem.9b01348. Epub 2019 Nov 8. J Med Chem. 2019. PMID: 31670517

6

Discovery of 3-(4-(2-((1H-Indol-5-yl)amino)-5-fluoropyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile Derivatives as Selective TYK2 Inhibitors for the Treatment of Inflammatory Bowel Disease.

Zhang C, Qi W, Li Y, Tang M, Yang T, Liu K, Chen Y, Deng D, Xiang M, Chen L. Zhang C, et al. Among authors: qi w. J Med Chem. 2021 Feb 25;64(4):1966-1988. doi: 10.1021/acs.jmedchem.0c01468. Epub 2021 Feb 16. J Med Chem. 2021. PMID: 33593051

7

A size-shrinkable matrix metallopeptidase-2-sensitive delivery nanosystem improves the penetration of human programmed death-ligand 1 siRNA into lung-tumor spheroids.

Wen J, Qiu N, Zhu Z, Bai P, Hu M, Qi W, Liu Y, Wei A, Chen L. Wen J, et al. Among authors: qi w. Drug Deliv. 2021 Dec;28(1):1055-1066. doi: 10.1080/10717544.2021.1931560. Drug Deliv. 2021. PMID: 34078185 Free PMC article.

8

Correction to "N-(Pyrimidin-2-yl)-1,2,3,4-tetrahydroisoquinolin-6-amine Derivatives as Selective Janus Kinase 2 Inhibitors for the Treatment of Myeloproliferative Neoplasms".

Yang T, Hu M, Chen Y, Xiang M, Tang M, Qi W, Shi M, He J, Yuan X, Zhang C, Liu K, Li J, Yang Z, Chen L. Yang T, et al. Among authors: qi w. J Med Chem. 2021 Feb 25;64(4):2310. doi: 10.1021/acs.jmedchem.1c00198. Epub 2021 Feb 16. J Med Chem. 2021. PMID: 33591746 No abstract available.

9

Correction to "Discovery of Potent and Orally Effective Dual Janus Kinase 2/FLT3 Inhibitors for the Treatment of Acute Myelogenous Leukemia and Myeloproliferative Neoplasms".

Yang T, Hu M, Qi W, Yang Z, Tang M, He J, Chen Y, Bai P, Yuan X, Zhang C, Liu K, Lu Y, Xiang M, Chen L. Yang T, et al. Among authors: qi w. J Med Chem. 2020 Feb 13;63(3):1441-1442. doi: 10.1021/acs.jmedchem.0c00025. Epub 2020 Jan 27. J Med Chem. 2020. PMID: 31985218 No abstract available.

10

Hand grip strength and all-cause mortality risk in individuals with decreased bone mass: a study from NHANES database.

Sun H, Liu J, Tan R, Zhang X, Qian X, Qi C, Qi W. Sun H, et al. Among authors: qi w. Front Med (Lausanne). 2024 Dec 11;11:1452811. doi: 10.3389/fmed.2024.1452811. eCollection 2024. Front Med (Lausanne). 2024. PMID: 39722828 Free PMC article.

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