He J - Search Results

1

The binding mechanism of NHWD-870 to bromodomain-containing protein 4 based on molecular dynamics simulations and free energy calculation.

Shi M, He J, Weng T, Shi N, Qi W, Guo Y, Chen T, Chen L, Xu D. Shi M, et al. Among authors: he j. Phys Chem Chem Phys. 2022 Feb 23;24(8):5125-5137. doi: 10.1039/d1cp05490b. Phys Chem Chem Phys. 2022. PMID: 35156677

2

Discovery of Novel Dual Histone Deacetylase and Mammalian Target of Rapamycin Target Inhibitors as a Promising Strategy for Cancer Therapy.

Chen Y, Yuan X, Zhang W, Tang M, Zheng L, Wang F, Yan W, Yang S, Wei Y, He J, Chen L. Chen Y, et al. Among authors: he j. J Med Chem. 2019 Feb 14;62(3):1577-1592. doi: 10.1021/acs.jmedchem.8b01825. Epub 2019 Jan 24. J Med Chem. 2019. PMID: 30629434

3

Design, synthesis and evaluation of novel 7H-pyrrolo[2,3-d]pyrimidin-4-amine derivatives as potent, selective and reversible Bruton's tyrosine kinase (BTK) inhibitors for the treatment of rheumatoid arthritis.

Zhang C, Pei H, He J, Zhu J, Li W, Niu T, Xiang M, Chen L. Zhang C, et al. Among authors: he j. Eur J Med Chem. 2019 May 1;169:121-143. doi: 10.1016/j.ejmech.2019.02.077. Epub 2019 Mar 6. Eur J Med Chem. 2019. PMID: 30875504

4

Discovery of Potent and Orally Effective Dual Janus Kinase 2/FLT3 Inhibitors for the Treatment of Acute Myelogenous Leukemia and Myeloproliferative Neoplasms.

Yang T, Hu M, Qi W, Yang Z, Tang M, He J, Chen Y, Bai P, Yuan X, Zhang C, Liu K, Lu Y, Xiang M, Chen L. Yang T, et al. Among authors: he j. J Med Chem. 2019 Nov 27;62(22):10305-10320. doi: 10.1021/acs.jmedchem.9b01348. Epub 2019 Nov 8. J Med Chem. 2019. PMID: 31670517

5

Correction to "Discovery of Potent and Orally Effective Dual Janus Kinase 2/FLT3 Inhibitors for the Treatment of Acute Myelogenous Leukemia and Myeloproliferative Neoplasms".

Yang T, Hu M, Qi W, Yang Z, Tang M, He J, Chen Y, Bai P, Yuan X, Zhang C, Liu K, Lu Y, Xiang M, Chen L. Yang T, et al. Among authors: he j. J Med Chem. 2020 Feb 13;63(3):1441-1442. doi: 10.1021/acs.jmedchem.0c00025. Epub 2020 Jan 27. J Med Chem. 2020. PMID: 31985218 No abstract available.

6

N-(Pyrimidin-2-yl)-1,2,3,4-tetrahydroisoquinolin-6-amine Derivatives as Selective Janus Kinase 2 Inhibitors for the Treatment of Myeloproliferative Neoplasms.

Yang T, Hu M, Chen Y, Xiang M, Tang M, Qi W, Shi M, He J, Yuan X, Zhang C, Liu K, Li J, Yang Z, Chen L. Yang T, et al. Among authors: he j. J Med Chem. 2020 Dec 10;63(23):14921-14936. doi: 10.1021/acs.jmedchem.0c01488. Epub 2020 Nov 30. J Med Chem. 2020. PMID: 33256400

7

Correction to "N-(Pyrimidin-2-yl)-1,2,3,4-tetrahydroisoquinolin-6-amine Derivatives as Selective Janus Kinase 2 Inhibitors for the Treatment of Myeloproliferative Neoplasms".

Yang T, Hu M, Chen Y, Xiang M, Tang M, Qi W, Shi M, He J, Yuan X, Zhang C, Liu K, Li J, Yang Z, Chen L. Yang T, et al. Among authors: he j. J Med Chem. 2021 Feb 25;64(4):2310. doi: 10.1021/acs.jmedchem.1c00198. Epub 2021 Feb 16. J Med Chem. 2021. PMID: 33591746 No abstract available.

8

Therapeutic efficacy of an injectable formulation of purinostat mesylate in SU-DHL-6 tumour model.

Zhu Z, Wen J, Xu Y, Pei H, Li D, Tang M, Bai P, He J, Yang Z, Chen L. Zhu Z, et al. Among authors: he j. Ann Med. 2022 Dec;54(1):743-753. doi: 10.1080/07853890.2022.2045347. Ann Med. 2022. PMID: 35243950 Free PMC article.

9

Molecular dynamics simulations of the conformational plasticity in the active pocket of salt-inducible kinase 2 (SIK2) multi-state binding with bosutinib.

Shi M, Wang L, Liu K, Chen Y, Hu M, Yang L, He J, Chen L, Xu D. Shi M, et al. Among authors: he j. Comput Struct Biotechnol J. 2022 May 23;20:2574-2586. doi: 10.1016/j.csbj.2022.05.039. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 35685353 Free PMC article.

10

Identification of Pyrrolo[2,3- d]pyrimidine-Based Derivatives as Potent and Orally Effective Fms-like Tyrosine Receptor Kinase 3 (FLT3) Inhibitors for Treating Acute Myelogenous Leukemia.

Yuan X, Chen Y, Zhang W, He J, Lei L, Tang M, Liu J, Li M, Dou C, Yang T, Yang L, Yang S, Wei Y, Peng A, Niu T, Xiang M, Ye H, Chen L. Yuan X, et al. Among authors: he j. J Med Chem. 2019 Apr 25;62(8):4158-4173. doi: 10.1021/acs.jmedchem.9b00223. Epub 2019 Apr 15. J Med Chem. 2019. PMID: 30939008

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

34,802 results

Search Page

Filters