Liang X - Search Results

1

Design, synthesis and biological evaluation of hydantoin derivatives as Mcl-1 selective inhibitors.

Liang X, Li X, Zhao Z, Nie Y, Yao Z, Ren W, Yang X, Hou X, Fang H. Liang X, et al. Bioorg Chem. 2022 Apr;121:105643. doi: 10.1016/j.bioorg.2022.105643. Epub 2022 Jan 25. Bioorg Chem. 2022. PMID: 35150958

2

Design, synthesis and biological evaluation of imidazolidine-2,4-dione and 2-thioxothiazolidin-4-one derivatives as lymphoid-specific tyrosine phosphatase inhibitors.

Liang X, Fu H, Xiao P, Fang H, Hou X. Liang X, et al. Bioorg Chem. 2020 Oct;103:104124. doi: 10.1016/j.bioorg.2020.104124. Epub 2020 Jul 23. Bioorg Chem. 2020. PMID: 32768742

3

Inhibition of striatal-enriched protein tyrosine phosphatase by targeting computationally revealed cryptic pockets.

Hou X, Sun JP, Ge L, Liang X, Li K, Zhang Y, Fang H. Hou X, et al. Among authors: liang x. Eur J Med Chem. 2020 Mar 15;190:112131. doi: 10.1016/j.ejmech.2020.112131. Epub 2020 Feb 11. Eur J Med Chem. 2020. PMID: 32078861 Free PMC article.

4

Structure, Function and Modulation of Striatal-enriched Protein Tyrosine Phosphatase (STEP).

Liang X, Hou X, Fang H. Liang X, et al. Curr Med Chem. 2021;28(37):7714-7728. doi: 10.2174/0929867328666210412123304. Curr Med Chem. 2021. PMID: 33845719 Review.

5

Computational Strategy for Bound State Structure Prediction in Structure-Based Virtual Screening: A Case Study of Protein Tyrosine Phosphatase Receptor Type O Inhibitors.

Hou X, Rooklin D, Yang D, Liang X, Li K, Lu J, Wang C, Xiao P, Zhang Y, Sun JP, Fang H. Hou X, et al. Among authors: liang x. J Chem Inf Model. 2018 Nov 26;58(11):2331-2342. doi: 10.1021/acs.jcim.8b00548. Epub 2018 Oct 19. J Chem Inf Model. 2018. PMID: 30299094 Free PMC article.

6

The discovery of indole derivatives as novel hepatitis C virus inhibitors.

Han Z, Liang X, Wang Y, Qing J, Cao L, Shang L, Yin Z. Han Z, et al. Among authors: liang x. Eur J Med Chem. 2016 Jun 30;116:147-155. doi: 10.1016/j.ejmech.2016.03.062. Epub 2016 Mar 26. Eur J Med Chem. 2016. PMID: 27061978

7

Discovery of novel 2-aryl-3-sulfonamido-pyridines (HoAns) as microtubule polymerization inhibitors with potent antitumor activities.

Zhu H, Ying S, Zhou B, Liang X, He Q, Song P, Hu X, Shi K, Xiong M, Jin H, Pan Y. Zhu H, et al. Among authors: liang x. Eur J Med Chem. 2021 Feb 5;211:113117. doi: 10.1016/j.ejmech.2020.113117. Epub 2020 Dec 25. Eur J Med Chem. 2021. PMID: 33360794

8

Design, synthesis, and evaluation of novel coumarin-dithiocarbamate derivatives (IDs) as anti-colorectal cancer agents.

Zhu H, Ying S, Zhou B, Hu X, Liang X, Li W, Wang D, Jin H, Pan Y. Zhu H, et al. Among authors: liang x. J Enzyme Inhib Med Chem. 2021 Dec;36(1):593-604. doi: 10.1080/14756366.2021.1875458. J Enzyme Inhib Med Chem. 2021. PMID: 33557648 Free PMC article.

9

Structurally novel PI3Kδ/γ dual inhibitors characterized by a seven-membered spirocyclic spacer: The SARs investigation and PK evaluation.

Tao Q, Chen Y, Liang X, Hu Y, Li J, Fang F, Wang H, Meng C, Liang J, Ma X, Gui S. Tao Q, et al. Among authors: liang x, liang j. Eur J Med Chem. 2020 Apr 1;191:112143. doi: 10.1016/j.ejmech.2020.112143. Epub 2020 Feb 17. Eur J Med Chem. 2020. PMID: 32078865

10

Dual Mechanism of an Intramolecular Charge Transfer (ICT)-FRET-Based Fluorescent Probe for the Selective Detection of Hydrogen Peroxide.

Liang X, Xu X, Qiao D, Yin Z, Shang L. Liang X, et al. Chem Asian J. 2017 Dec 14;12(24):3187-3194. doi: 10.1002/asia.201701382. Epub 2017 Nov 28. Chem Asian J. 2017. PMID: 29063729

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