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Page 1
Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus.
Wang S, Reeve SM, Holt GT, Ojewole AA, Frenkel MS, Gainza P, Keshipeddy S, Fowler VG, Wright DL, Donald BR. Wang S, et al. Among authors: wright dl. PLoS Comput Biol. 2022 Feb 10;18(2):e1009855. doi: 10.1371/journal.pcbi.1009855. eCollection 2022 Feb. PLoS Comput Biol. 2022. PMID: 35143481 Free PMC article.
Toward Broad Spectrum Dihydrofolate Reductase Inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin Resistant Staphylococcus aureus.
Reeve SM, Si D, Krucinska J, Yan Y, Viswanathan K, Wang S, Holt GT, Frenkel MS, Ojewole AA, Estrada A, Agabiti SS, Alverson JB, Gibson ND, Priestley ND, Wiemer AJ, Donald BR, Wright DL. Reeve SM, et al. Among authors: wright dl. ACS Infect Dis. 2019 Nov 8;5(11):1896-1906. doi: 10.1021/acsinfecdis.9b00222. Epub 2019 Oct 15. ACS Infect Dis. 2019. PMID: 31565920 Free PMC article.
Propargyl-linked antifolates are dual inhibitors of Candida albicans and Candida glabrata.
G-Dayanandan N, Paulsen JL, Viswanathan K, Keshipeddy S, Lombardo MN, Zhou W, Lamb KM, Sochia AE, Alverson JB, Priestley ND, Wright DL, Anderson AC. G-Dayanandan N, et al. Among authors: wright dl. J Med Chem. 2014 Mar 27;57(6):2643-56. doi: 10.1021/jm401916j. Epub 2014 Mar 6. J Med Chem. 2014. PMID: 24568657 Free PMC article.
MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates.
Reeve SM, Scocchera EW, G-Dayanadan N, Keshipeddy S, Krucinska J, Hajian B, Ferreira J, Nailor M, Aeschlimann J, Wright DL, Anderson AC. Reeve SM, et al. Among authors: wright dl. Cell Chem Biol. 2016 Dec 22;23(12):1458-1467. doi: 10.1016/j.chembiol.2016.11.007. Epub 2016 Dec 8. Cell Chem Biol. 2016. PMID: 27939900 Free PMC article.
283 results