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A SIMPLI (Single-cell Identification from MultiPLexed Images) approach for spatially-resolved tissue phenotyping at single-cell resolution.
Bortolomeazzi M, Montorsi L, Temelkovski D, Keddar MR, Acha-Sagredo A, Pitcher MJ, Basso G, Laghi L, Rodriguez-Justo M, Spencer J, Ciccarelli FD. Bortolomeazzi M, et al. Among authors: ciccarelli fd. Nat Commun. 2022 Feb 9;13(1):781. doi: 10.1038/s41467-022-28470-x. Nat Commun. 2022. PMID: 35140207 Free PMC article.
Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma.
Mourikis TP, Benedetti L, Foxall E, Temelkovski D, Nulsen J, Perner J, Cereda M, Lagergren J, Howell M, Yau C, Fitzgerald RC, Scaffidi P; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium; Ciccarelli FD. Mourikis TP, et al. Among authors: ciccarelli fd. Nat Commun. 2019 Jul 15;10(1):3101. doi: 10.1038/s41467-019-10898-3. Nat Commun. 2019. PMID: 31308377 Free PMC article.
Identification of non-cancer cells from cancer transcriptomic data.
Bortolomeazzi M, Keddar MR, Ciccarelli FD, Benedetti L. Bortolomeazzi M, et al. Among authors: ciccarelli fd. Biochim Biophys Acta Gene Regul Mech. 2020 Jun;1863(6):194445. doi: 10.1016/j.bbagrm.2019.194445. Epub 2019 Oct 22. Biochim Biophys Acta Gene Regul Mech. 2020. PMID: 31654804 Free PMC article. Review.
Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts.
Bortolomeazzi M, Keddar MR, Montorsi L, Acha-Sagredo A, Benedetti L, Temelkovski D, Choi S, Petrov N, Todd K, Wai P, Kohl J, Denner T, Nye E, Goldstone R, Ward S, Wilson GA, Al Bakir M, Swanton C, John S, Miles J, Larijani B, Kunene V, Fontana E, Arkenau HT, Parker PJ, Rodriguez-Justo M, Shiu KK, Spencer J, Ciccarelli FD. Bortolomeazzi M, et al. Among authors: ciccarelli fd. Gastroenterology. 2021 Oct;161(4):1179-1193. doi: 10.1053/j.gastro.2021.06.064. Epub 2021 Jun 29. Gastroenterology. 2021. PMID: 34197832 Free PMC article.
Clone competition as a mechanism to reduce tumor formation.
Acha-Sagredo A, Malanchi I, Ciccarelli FD. Acha-Sagredo A, et al. Among authors: ciccarelli fd. Dev Cell. 2021 Dec 20;56(24):3307-3308. doi: 10.1016/j.devcel.2021.12.003. Dev Cell. 2021. PMID: 34932947 Free article.
Comparative assessment of genes driving cancer and somatic evolution in non-cancer tissues: an update of the Network of Cancer Genes (NCG) resource.
Dressler L, Bortolomeazzi M, Keddar MR, Misetic H, Sartini G, Acha-Sagredo A, Montorsi L, Wijewardhane N, Repana D, Nulsen J, Goldman J, Pollitt M, Davis P, Strange A, Ambrose K, Ciccarelli FD. Dressler L, et al. Among authors: ciccarelli fd. Genome Biol. 2022 Jan 26;23(1):35. doi: 10.1186/s13059-022-02607-z. Genome Biol. 2022. PMID: 35078504 Free PMC article. Review.
87 results