Kihara Y - Search Results

1

Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate.

Liu S, Paknejad N, Zhu L, Kihara Y, Ray M, Chun J, Liu W, Hite RK, Huang XY. Liu S, et al. Among authors: kihara y. Nat Commun. 2022 Feb 8;13(1):731. doi: 10.1038/s41467-022-28417-2. Nat Commun. 2022. PMID: 35136060 Free PMC article.

2

Lysophosphatidic acid (LPA)-antibody (504B3) engagement detected by interferometry identifies off-target binding.

Ray M, Kihara Y, Bornhop DJ, Chun J. Ray M, et al. Among authors: kihara y. Lipids Health Dis. 2021 Apr 14;20(1):32. doi: 10.1186/s12944-021-01454-4. Lipids Health Dis. 2021. PMID: 33853612 Free PMC article.

3

Fingolimod: direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy.

Groves A, Kihara Y, Chun J. Groves A, et al. Among authors: kihara y. J Neurol Sci. 2013 May 15;328(1-2):9-18. doi: 10.1016/j.jns.2013.02.011. Epub 2013 Mar 19. J Neurol Sci. 2013. PMID: 23518370 Free PMC article. Review.

4

Lysophospholipid receptors in drug discovery.

Kihara Y, Mizuno H, Chun J. Kihara Y, et al. Exp Cell Res. 2015 May 1;333(2):171-177. doi: 10.1016/j.yexcr.2014.11.020. Epub 2014 Dec 8. Exp Cell Res. 2015. PMID: 25499971 Free PMC article. Review.

5

Lysophospholipid G protein-coupled receptor binding parameters as determined by backscattering interferometry.

Mizuno H, Kihara Y, Kussrow A, Chen A, Ray M, Rivera R, Bornhop DJ, Chun J. Mizuno H, et al. Among authors: kihara y. J Lipid Res. 2019 Jan;60(1):212-217. doi: 10.1194/jlr.D089938. Epub 2018 Nov 21. J Lipid Res. 2019. PMID: 30463988 Free PMC article.

6

Fingolimod: Lessons Learned and New Opportunities for Treating Multiple Sclerosis and Other Disorders.

Chun J, Kihara Y, Jonnalagadda D, Blaho VA. Chun J, et al. Among authors: kihara y. Annu Rev Pharmacol Toxicol. 2019 Jan 6;59:149-170. doi: 10.1146/annurev-pharmtox-010818-021358. Annu Rev Pharmacol Toxicol. 2019. PMID: 30625282 Free PMC article. Review.

7

Unlabeled lysophosphatidic acid receptor binding in free solution as determined by a compensated interferometric reader.

Ray M, Nagai K, Kihara Y, Kussrow A, Kammer MN, Frantz A, Bornhop DJ, Chun J. Ray M, et al. Among authors: kihara y. J Lipid Res. 2020 Aug;61(8):1244-1251. doi: 10.1194/jlr.D120000880. Epub 2020 Jun 8. J Lipid Res. 2020. PMID: 32513900 Free PMC article.

8

S1P₂-Gα₁₂ Signaling Controls Astrocytic Glutamate Uptake and Mitochondrial Oxygen Consumption.

Jonnalagadda D, Kihara Y, Rivera R, Chun J. Jonnalagadda D, et al. Among authors: kihara y. eNeuro. 2021 Jul 16;8(4):ENEURO.0040-21.2021. doi: 10.1523/ENEURO.0040-21.2021. Print 2021 Jul-Aug. eNeuro. 2021. PMID: 33893167 Free PMC article.

9

Ponesimod inhibits astrocyte-mediated neuroinflammation and protects against cingulum demyelination via S1P₁ -selective modulation.

Kihara Y, Jonnalagadda D, Zhu Y, Ray M, Ngo T, Palmer C, Rivera R, Chun J. Kihara Y, et al. FASEB J. 2022 Feb;36(2):e22132. doi: 10.1096/fj.202101531R. FASEB J. 2022. PMID: 34986275 Free PMC article.

10

Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA₂), UCM-14216, Ameliorates Spinal Cord Injury in Mice.

Khiar-Fernández N, Zian D, Vázquez-Villa H, Martínez RF, Escobar-Peña A, Foronda-Sainz R, Ray M, Puigdomenech-Poch M, Cincilla G, Sánchez-Martínez M, Kihara Y, Chun J, López-Vales R, López-Rodríguez ML, Ortega-Gutiérrez S. Khiar-Fernández N, et al. Among authors: kihara y. J Med Chem. 2022 Aug 25;65(16):10956-10974. doi: 10.1021/acs.jmedchem.2c00046. Epub 2022 Aug 10. J Med Chem. 2022. PMID: 35948083 Free PMC article.

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