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Page 1
Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance.
Skovsø S, Panzhinskiy E, Kolic J, Cen HH, Dionne DA, Dai XQ, Sharma RB, Elghazi L, Ellis CE, Faulkner K, Marcil SAM, Overby P, Noursadeghi N, Hutchinson D, Hu X, Li H, Modi H, Wildi JS, Botezelli JD, Noh HL, Suk S, Gablaski B, Bautista A, Kim R, Cras-Méneur C, Flibotte S, Sinha S, Luciani DS, Nislow C, Rideout EJ, Cytrynbaum EN, Kim JK, Bernal-Mizrachi E, Alonso LC, MacDonald PE, Johnson JD. Skovsø S, et al. Among authors: ellis ce. Nat Commun. 2022 Feb 8;13(1):735. doi: 10.1038/s41467-022-28039-8. Nat Commun. 2022. PMID: 35136059 Free PMC article.
AAV GCG-EGFP, a new tool to identify glucagon-secreting α-cells.
Tudurí E, Glavas MM, Asadi A, Baker RK, Ellis CE, Soukhatcheva G, Philit M, Huynh FK, Johnson JD, Bruce Verchere C, Kieffer TJ. Tudurí E, et al. Among authors: ellis ce. Sci Rep. 2019 Jul 25;9(1):10829. doi: 10.1038/s41598-019-46735-2. Sci Rep. 2019. PMID: 31346189 Free PMC article.
Role of myeloid cell leptin signaling in the regulation of glucose metabolism.
Pereira S, Cline DL, Chan M, Chai K, Yoon JS, O'Dwyer SM, Ellis CE, Glavas MM, Webber TD, Baker RK, Erener S, Covey SD, Kieffer TJ. Pereira S, et al. Among authors: ellis ce. Sci Rep. 2021 Sep 15;11(1):18394. doi: 10.1038/s41598-021-97549-0. Sci Rep. 2021. PMID: 34526546 Free PMC article.
Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice.
Erener S, Ellis CE, Ramzy A, Glavas MM, O'Dwyer S, Pereira S, Wang T, Pang J, Bruin JE, Riedel MJ, Baker RK, Webber TD, Lesina M, Blüher M, Algül H, Kopp JL, Herzig S, Kieffer TJ. Erener S, et al. Among authors: ellis ce. Cell Rep Med. 2021 Nov 11;2(11):100434. doi: 10.1016/j.xcrm.2021.100434. eCollection 2021 Nov 16. Cell Rep Med. 2021. PMID: 34841287 Free PMC article.
From Isles of Königsberg to Islets of Langerhans: Examining the Function of the Endocrine Pancreas Through Network Science.
Stožer A, Šterk M, Paradiž Leitgeb E, Markovič R, Skelin Klemen M, Ellis CE, Križančić Bombek L, Dolenšek J, MacDonald PE, Gosak M. Stožer A, et al. Among authors: ellis ce. Front Endocrinol (Lausanne). 2022 Jun 15;13:922640. doi: 10.3389/fendo.2022.922640. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35784543 Free PMC article. Review.
Dynamic Ins2 Gene Activity Defines β-Cell Maturity States.
Chu CMJ, Modi H, Ellis C, Krentz NAJ, Skovsø S, Zhao YB, Cen H, Noursadeghi N, Panzhinskiy E, Hu X, Dionne DA, Xia YH, Xuan S, Huising MO, Kieffer TJ, Lynn FC, Johnson JD. Chu CMJ, et al. Diabetes. 2022 Dec 1;71(12):2612-2631. doi: 10.2337/db21-1065. Diabetes. 2022. PMID: 36170671
Integration of single-cell multiomic measurements across disease states with genetics identifies mechanisms of beta cell dysfunction in type 2 diabetes.
Wang G, Chiou J, Zeng C, Miller M, Matta I, Han JY, Kadakia N, Okino ML, Beebe E, Mallick M, Camunas-Soler J, Dos Santos T, Dai XQ, Ellis C, Hang Y, Kim SK, MacDonald PE, Kandeel FR, Preissl S, Gaulton KJ, Sander M. Wang G, et al. bioRxiv [Preprint]. 2023 Jan 2:2022.12.31.522386. doi: 10.1101/2022.12.31.522386. bioRxiv. 2023. Update in: Nat Genet. 2023 Jun;55(6):984-994. doi: 10.1038/s41588-023-01397-9 PMID: 36711922 Free PMC article. Updated. Preprint.
Human A2-CAR T cells reject HLA-A2+ human islets transplanted into mice without inducing graft versus host disease.
Ellis CE, Mojibian M, Ida S, Fung VCW, Skovsø S, McIver E, O'Dwyer S, Webber TD, Braam MJS, Saber N, Kieffer TJ, Levings MK. Ellis CE, et al. bioRxiv [Preprint]. 2023 Feb 23:2023.02.23.529741. doi: 10.1101/2023.02.23.529741. bioRxiv. 2023. Update in: Transplantation. 2023 Sep 1;107(9):e222-e233. doi: 10.1097/TP.0000000000004709 PMID: 36865123 Free PMC article. Updated. Preprint.
Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes.
Wang G, Chiou J, Zeng C, Miller M, Matta I, Han JY, Kadakia N, Okino ML, Beebe E, Mallick M, Camunas-Soler J, Dos Santos T, Dai XQ, Ellis C, Hang Y, Kim SK, MacDonald PE, Kandeel FR, Preissl S, Gaulton KJ, Sander M. Wang G, et al. Nat Genet. 2023 Jun;55(6):984-994. doi: 10.1038/s41588-023-01397-9. Epub 2023 May 25. Nat Genet. 2023. PMID: 37231096 Free PMC article.
75 results