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Page 1
Measurement of neutral ceramidase activity in vitro and in vivo.
Simoes M, Saleh A, Choi YM, Airola MV, Haley JD, Coant N. Simoes M, et al. Among authors: coant n. Anal Biochem. 2022 Apr 15;643:114577. doi: 10.1016/j.ab.2022.114577. Epub 2022 Feb 5. Anal Biochem. 2022. PMID: 35134389 Review.
Role of neutral ceramidase in colon cancer.
García-Barros M, Coant N, Kawamori T, Wada M, Snider AJ, Truman JP, Wu BX, Furuya H, Clarke CJ, Bialkowska AB, Ghaleb A, Yang VW, Obeid LM, Hannun YA. García-Barros M, et al. Among authors: coant n. FASEB J. 2016 Dec;30(12):4159-4171. doi: 10.1096/fj.201600611R. Epub 2016 Sep 8. FASEB J. 2016. PMID: 27609772 Free PMC article.
Taken together, these studies show that nCDase is pivotal for regulating initiation and development of colon cancer, and these data suggest that this enzyme is a suitable and novel target for colon cancer therapy.-Garcia-Barros, M., Coant, N., Kawamori, T., Wada, M. …
Taken together, these studies show that nCDase is pivotal for regulating initiation and development of colon cancer, and these data suggest …
Functions of neutral ceramidase in the Golgi apparatus.
Sakamoto W, Coant N, Canals D, Obeid LM, Hannun YA. Sakamoto W, et al. Among authors: coant n. J Lipid Res. 2018 Nov;59(11):2116-2125. doi: 10.1194/jlr.M088187. Epub 2018 Aug 28. J Lipid Res. 2018. PMID: 30154232 Free PMC article.
Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening.
Otsuka Y, Airola MV, Choi YM, Coant N, Snider J, Cariello C, Saied EM, Arenz C, Bannister T, Rahaim R Jr, Hannun YA, Shumate J, Scampavia L, Haley JD, Spicer TP. Otsuka Y, et al. Among authors: coant n. SLAS Discov. 2021 Jan;26(1):113-121. doi: 10.1177/2472555220945283. Epub 2020 Jul 31. SLAS Discov. 2021. PMID: 32734807 Free PMC article.
Loss of acid ceramidase in myeloid cells suppresses intestinal neutrophil recruitment.
Espaillat MP, Snider AJ, Qiu Z, Channer B, Coant N, Schuchman EH, Kew RR, Sheridan BS, Hannun YA, Obeid LM. Espaillat MP, et al. Among authors: coant n. FASEB J. 2018 May;32(5):2339-2353. doi: 10.1096/fj.201700585R. Epub 2017 Dec 19. FASEB J. 2018. PMID: 29259036 Free PMC article.
P., Snider, A. J., Qiu, Z., Channer, B., Coant, N., Schuchman, E. H., Kew, R. R., Sheridan, B. S., Hannun, Y. A., Obeid, L. M. ...
P., Snider, A. J., Qiu, Z., Channer, B., Coant, N., Schuchman, E. H., Kew, R. R., Sheridan, B. S., Hannun, Y. A., Obeid, L. M. …
32 results