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393 results

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Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors.
Keshet R, Lee JS, Adler L, Iraqi M, Ariav Y, Lim LQJ, Lerner S, Rabinovich S, Oren R, Katzir R, Weiss Tishler H, Stettner N, Goldman O, Landesman H, Galai S, Kuperman Y, Kuznetsov Y, Brandis A, Mehlman T, Malitsky S, Itkin M, Koehler SE, Zhao Y, Talsania K, Shen TW, Peled N, Ulitsky I, Porgador A, Ruppin E, Erez A. Keshet R, et al. Among authors: oren r. Nat Cancer. 2020 Sep;1(9):894-908. doi: 10.1038/s43018-020-0106-7. Epub 2020 Aug 31. Nat Cancer. 2020. PMID: 35121952
Sulfamate Acetamides as Self-Immolative Electrophiles for Covalent Ligand-Directed Release Chemistry.
Reddi RN, Rogel A, Gabizon R, Rawale DG, Harish B, Marom S, Tivon B, Arbel YS, Gurwicz N, Oren R, David K, Liu J, Duberstein S, Itkin M, Malitsky S, Barr H, Katz BZ, Herishanu Y, Shachar I, Shulman Z, London N. Reddi RN, et al. Among authors: oren r. J Am Chem Soc. 2023 Feb 15;145(6):3346-3360. doi: 10.1021/jacs.2c08853. Epub 2023 Feb 4. J Am Chem Soc. 2023. PMID: 36738297 Free PMC article.
Early Infiltration of Innate Immune Cells to the Liver Depletes HNF4α and Promotes Extrahepatic Carcinogenesis.
Goldman O, Adler LN, Hajaj E, Croese T, Darzi N, Galai S, Tishler H, Ariav Y, Lavie D, Fellus-Alyagor L, Oren R, Kuznetsov Y, David E, Jaschek R, Stossel C, Singer O, Malitsky S, Barak R, Seger R, Erez N, Amit I, Tanay A, Saada A, Golan T, Rubinek T, Sang Lee J, Ben-Shachar S, Wolf I, Erez A. Goldman O, et al. Among authors: oren r. Cancer Discov. 2023 Jul 7;13(7):1616-1635. doi: 10.1158/2159-8290.CD-22-1062. Cancer Discov. 2023. PMID: 36972357 Free PMC article.
Establishing a Mouse Genotyping Core Facility Based on Automation, High-resolution Melting Analysis, and Purpose-developed MATLAB Applications for Sample Tracking, Data Analysis, and Report Generation.
Dafni H, Levi K, Eldad MC, Shaul M, Oren R, Alyagor L, Stettner N, Harmelin A, Haffner-Krausz R. Dafni H, et al. Among authors: oren r. Comp Med. 2024 Aug 1;74(4):263-273. doi: 10.30802/AALAS-CM-24-000014. Epub 2024 May 25. Comp Med. 2024. PMID: 38796303 Free article.
Temporal genomic analysis of homogeneous tumor models reveals key regulators of immune evasion in melanoma.
Cohen Shvefel S, Pai JA, Cao Y, Pal LR, Bartok O, Levy R, Zemanek MJ, Weller C, Herzog E, Yao W, Hiam-Galvez KJ, Cheng K, Yin Y, Du PP, Raposo CJ, Gumpert N, Welti M, Martínez Gómez JM, Sella F, Yakubovich E, Orr I, Ben-Dor S, Oren R, Fellus-Alyagor L, Golani O, Brenner OJ, Salame TM, Zerbib M, Goliand I, Ranmar D, Savchenko I, Ketrarou N, Schaffer AA, Dahan R, Levesque MP, Ruppin E, Satpathy AT, Samuels Y. Cohen Shvefel S, et al. Among authors: oren r. Cancer Discov. 2024 Nov 20. doi: 10.1158/2159-8290.CD-23-1422. Online ahead of print. Cancer Discov. 2024. PMID: 39715301
Imaging aspects of the tumor stroma with therapeutic implications.
Narunsky L, Oren R, Bochner F, Neeman M. Narunsky L, et al. Among authors: oren r. Pharmacol Ther. 2014 Feb;141(2):192-208. doi: 10.1016/j.pharmthera.2013.10.003. Epub 2013 Oct 14. Pharmacol Ther. 2014. PMID: 24134903 Free PMC article. Review.
393 results