Kapoor T - Search Results

1

Renin-Angiotensin-Aldosterone System Inhibitors and the Risk of AKI in COVID-19 Compared with Influenza.

Birkelo BC, Parr SK, Perkins AM, Greevy RA Jr, Arroyo JP, Hung AM, Vincz AJ, Shah SC, Kapoor T, Matheny ME, Siew ED. Birkelo BC, et al. Among authors: kapoor t. Clin J Am Soc Nephrol. 2022 Mar;17(3):423-425. doi: 10.2215/CJN.11190821. Epub 2022 Feb 2. Clin J Am Soc Nephrol. 2022. PMID: 35110376 Free PMC article. No abstract available.

2

Designing Allele-Specific Inhibitors of Spastin, a Microtubule-Severing AAA Protein.

Pisa R, Cupido T, Kapoor TM. Pisa R, et al. Among authors: kapoor tm. J Am Chem Soc. 2019 Apr 10;141(14):5602-5606. doi: 10.1021/jacs.8b13257. Epub 2019 Mar 27. J Am Chem Soc. 2019. PMID: 30875216 Free PMC article.

3

A chemical genetics approach to examine the functions of AAA proteins.

Cupido T, Jones NH, Grasso MJ, Pisa R, Kapoor TM. Cupido T, et al. Among authors: kapoor tm. Nat Struct Mol Biol. 2021 Apr;28(4):388-397. doi: 10.1038/s41594-021-00575-9. Epub 2021 Mar 29. Nat Struct Mol Biol. 2021. PMID: 33782614 Free PMC article.

4

Designing a chemical inhibitor for the AAA protein spastin using active site mutations.

Cupido T, Pisa R, Kelley ME, Kapoor TM. Cupido T, et al. Among authors: kapoor tm. Nat Chem Biol. 2019 May;15(5):444-452. doi: 10.1038/s41589-019-0225-6. Epub 2019 Feb 18. Nat Chem Biol. 2019. PMID: 30778202 Free PMC article.

5

Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins.

Pisa R, Cupido T, Steinman JB, Jones NH, Kapoor TM. Pisa R, et al. Among authors: kapoor tm. Cell Chem Biol. 2019 Sep 19;26(9):1263-1273.e5. doi: 10.1016/j.chembiol.2019.06.001. Epub 2019 Jun 27. Cell Chem Biol. 2019. PMID: 31257183 Free PMC article.

6

Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity.

See SK, Hoogendoorn S, Chung AH, Ye F, Steinman JB, Sakata-Kato T, Miller RM, Cupido T, Zalyte R, Carter AP, Nachury MV, Kapoor TM, Chen JK. See SK, et al. Among authors: kapoor tm. ACS Chem Biol. 2016 Jan 15;11(1):53-60. doi: 10.1021/acschembio.5b00895. Epub 2015 Nov 11. ACS Chem Biol. 2016. PMID: 26555042 Free PMC article.

7

Chemical strategies to overcome resistance against targeted anticancer therapeutics.

Pisa R, Kapoor TM. Pisa R, et al. Nat Chem Biol. 2020 Aug;16(8):817-825. doi: 10.1038/s41589-020-0596-8. Epub 2020 Jul 21. Nat Chem Biol. 2020. PMID: 32694636 Free PMC article. Review.

8

Distinct Mechanisms of Resistance to a CENP-E Inhibitor Emerge in Near-Haploid and Diploid Cancer Cells.

Pisa R, Phua DYZ, Kapoor TM. Pisa R, et al. Cell Chem Biol. 2020 Jul 16;27(7):850-857.e6. doi: 10.1016/j.chembiol.2020.05.003. Epub 2020 May 21. Cell Chem Biol. 2020. PMID: 32442423 Free PMC article.

9

Examining the mechanism of action of a kinesin inhibitor using stable isotope labeled inhibitors for cross-linking (SILIC).

Wacker SA, Kashyap S, Li X, Kapoor TM. Wacker SA, et al. J Am Chem Soc. 2011 Aug 17;133(32):12386-9. doi: 10.1021/ja204561q. Epub 2011 Jul 21. J Am Chem Soc. 2011. PMID: 21761885 Free PMC article.

10

Site-specific chemistry on the microtubule polymer.

Kleiner RE, Ti SC, Kapoor TM. Kleiner RE, et al. J Am Chem Soc. 2013 Aug 28;135(34):12520-3. doi: 10.1021/ja405199h. Epub 2013 Aug 15. J Am Chem Soc. 2013. PMID: 23930594 Free PMC article.

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