Sinkkonen L - Search Results

1

Park7 deletion leads to sex-specific transcriptome changes involving NRF2-CYP1B1 axis in mouse midbrain astrocytes.

Helgueta S, Heurtaux T, Sciortino A, Gui Y, Ohnmacht J, Mencke P, Boussaad I, Halder R, Garcia P, Krüger R, Mittelbronn M, Buttini M, Sauter T, Sinkkonen L. Helgueta S, et al. Among authors: sinkkonen l. NPJ Parkinsons Dis. 2025 Jan 4;11(1):8. doi: 10.1038/s41531-024-00851-7. NPJ Parkinsons Dis. 2025. PMID: 39755720 Free PMC article.

2

Epigenetic control of metabolic identity across cell types.

Pacheco MP, Gerard D, Mangan RJ, Chapman AR, Hecker D, Kellis M, Schulz MH, Sinkkonen L, Sauter T. Pacheco MP, et al. Among authors: sinkkonen l. bioRxiv [Preprint]. 2024 Dec 17:2024.07.24.604914. doi: 10.1101/2024.07.24.604914. bioRxiv. 2024. PMID: 39091778 Free PMC article. Preprint.

3

Multiomics analysis identifies novel facilitators of human dopaminergic neuron differentiation.

Gomez Ramos B, Ohnmacht J, de Lange N, Valceschini E, Ginolhac A, Catillon M, Ferrante D, Rakovic A, Halder R, Massart F, Arena G, Antony P, Bolognin S, Klein C, Krause R, Schulz MH, Sauter T, Krüger R, Sinkkonen L. Gomez Ramos B, et al. Among authors: sinkkonen l. EMBO Rep. 2024 Jan;25(1):254-285. doi: 10.1038/s44319-023-00024-2. Epub 2023 Dec 19. EMBO Rep. 2024. PMID: 38177910 Free PMC article.

4

2-Hydroxyglutarate modulates histone methylation at specific loci and alters gene expression via Rph1 inhibition.

Gavriil M, Proietto M, Paczia N, Ginolhac A, Halder R, Valceschini E, Sauter T, Linster CL, Sinkkonen L. Gavriil M, et al. Among authors: sinkkonen l. Life Sci Alliance. 2023 Nov 27;7(2):e202302333. doi: 10.26508/lsa.202302333. Print 2024 Feb. Life Sci Alliance. 2023. PMID: 38011998 Free PMC article.

5

Metabolic modelling-based in silico drug target prediction identifies six novel repurposable drugs for melanoma.

Bintener T, Pacheco MP, Philippidou D, Margue C, Kishk A, Del Mistro G, Di Leo L, Moscardó Garcia M, Halder R, Sinkkonen L, De Zio D, Kreis S, Kulms D, Sauter T. Bintener T, et al. Among authors: sinkkonen l. Cell Death Dis. 2023 Jul 26;14(7):468. doi: 10.1038/s41419-023-05955-1. Cell Death Dis. 2023. PMID: 37495601 Free PMC article.

6

Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions.

Soriano-Baguet L, Grusdat M, Kurniawan H, Benzarti M, Binsfeld C, Ewen A, Longworth J, Bonetti L, Guerra L, Franchina DG, Kobayashi T, Horkova V, Verschueren C, Helgueta S, Gérard D, More TH, Henne A, Dostert C, Farinelle S, Lesur A, Gérardy JJ, Jäger C, Mittelbronn M, Sinkkonen L, Hiller K, Meiser J, Brenner D. Soriano-Baguet L, et al. Among authors: sinkkonen l. Cell Rep. 2023 Mar 28;42(3):112153. doi: 10.1016/j.celrep.2023.112153. Epub 2023 Feb 26. Cell Rep. 2023. PMID: 36848289 Free article.

7

Review of Current Human Genome-Scale Metabolic Models for Brain Cancer and Neurodegenerative Diseases.

Kishk A, Pacheco MP, Heurtaux T, Sinkkonen L, Pang J, Fritah S, Niclou SP, Sauter T. Kishk A, et al. Among authors: sinkkonen l. Cells. 2022 Aug 10;11(16):2486. doi: 10.3390/cells11162486. Cells. 2022. PMID: 36010563 Free PMC article. Review.

8

Normal and Pathological NRF2 Signalling in the Central Nervous System.

Heurtaux T, Bouvier DS, Benani A, Helgueta Romero S, Frauenknecht KBM, Mittelbronn M, Sinkkonen L. Heurtaux T, et al. Among authors: sinkkonen l. Antioxidants (Basel). 2022 Jul 22;11(8):1426. doi: 10.3390/antiox11081426. Antioxidants (Basel). 2022. PMID: 35892629 Free PMC article. Review.

9

Fusion Dynamics of Hybrid Cell-Microparticle Aggregates: A Jelly Pearl Model.

Beaune G, Sinkkonen L, Gonzalez-Rodriguez D, Timonen JVI, Brochard-Wyart F. Beaune G, et al. Among authors: sinkkonen l. Langmuir. 2022 May 3;38(17):5296-5306. doi: 10.1021/acs.langmuir.1c02949. Epub 2022 Feb 3. Langmuir. 2022. PMID: 35109658 Free article.

10

Focal adhesion kinase plays a dual role in TRAIL resistance and metastatic outgrowth of malignant melanoma.

Del Mistro G, Riemann S, Schindler S, Beissert S, Kontermann RE, Ginolhac A, Halder R, Presta L, Sinkkonen L, Sauter T, Kulms D. Del Mistro G, et al. Among authors: sinkkonen l. Cell Death Dis. 2022 Jan 12;13(1):54. doi: 10.1038/s41419-022-04502-8. Cell Death Dis. 2022. PMID: 35022419 Free PMC article.

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