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Page 1
Suppressive effects of the obese tumor microenvironment on CD8 T cell infiltration and effector function.
Dyck L, Prendeville H, Raverdeau M, Wilk MM, Loftus RM, Douglas A, McCormack J, Moran B, Wilkinson M, Mills EL, Doughty M, Fabre A, Heneghan H, LeRoux C, Hogan A, Chouchani ET, O'Shea D, Brennan D, Lynch L. Dyck L, et al. Among authors: prendeville h. J Exp Med. 2022 Mar 7;219(3):e20210042. doi: 10.1084/jem.20210042. Epub 2022 Feb 1. J Exp Med. 2022. PMID: 35103755 Free PMC article.
Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments.
Lopes N, McIntyre C, Martin S, Raverdeau M, Sumaria N, Kohlgruber AC, Fiala GJ, Agudelo LZ, Dyck L, Kane H, Douglas A, Cunningham S, Prendeville H, Loftus R, Carmody C, Pierre P, Kellis M, Brenner M, Argüello RJ, Silva-Santos B, Pennington DJ, Lynch L. Lopes N, et al. Among authors: prendeville h. Nat Immunol. 2021 Feb;22(2):179-192. doi: 10.1038/s41590-020-00848-3. Epub 2021 Jan 18. Nat Immunol. 2021. PMID: 33462452 Free PMC article.
UCP1 governs liver extracellular succinate and inflammatory pathogenesis.
Mills EL, Harmon C, Jedrychowski MP, Xiao H, Garrity R, Tran NV, Bradshaw GA, Fu A, Szpyt J, Reddy A, Prendeville H, Danial NN, Gygi SP, Lynch L, Chouchani ET. Mills EL, et al. Among authors: prendeville h. Nat Metab. 2021 May;3(5):604-617. doi: 10.1038/s42255-021-00389-5. Epub 2021 May 17. Nat Metab. 2021. PMID: 34002097 Free PMC article. Review.
Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation.
Mills EL, Harmon C, Jedrychowski MP, Xiao H, Gruszczyk AV, Bradshaw GA, Tran N, Garrity R, Laznik-Bogoslavski D, Szpyt J, Prendeville H, Lynch L, Murphy MP, Gygi SP, Spiegelman BM, Chouchani ET. Mills EL, et al. Among authors: prendeville h. Cell Metab. 2022 Jan 4;34(1):140-157.e8. doi: 10.1016/j.cmet.2021.11.003. Epub 2021 Dec 2. Cell Metab. 2022. PMID: 34861155 Free PMC article.
Diet, lipids, and antitumor immunity.
Prendeville H, Lynch L. Prendeville H, et al. Cell Mol Immunol. 2022 Mar;19(3):432-444. doi: 10.1038/s41423-021-00781-x. Epub 2022 Jan 5. Cell Mol Immunol. 2022. PMID: 34983949 Free PMC article. Review.
Correction: Suppressive effects of the obese tumor microenvironment on CD8 T cell infiltration and effector function.
Dyck L, Prendeville H, Raverdeau M, Wilk MM, Loftus RM, Douglas A, McCormack J, Moran B, Wilkinson M, Mills EL, Doughty M, Fabre A, Heneghan H, LeRoux C, Hogan A, Chouchani ET, O'Shea D, Brennan D, Lynch L. Dyck L, et al. Among authors: prendeville h. J Exp Med. 2022 Mar 7;219(3):jem.2021004202072022c. doi: 10.1084/jem.2021004202072022c. Epub 2022 Feb 28. J Exp Med. 2022. PMID: 35226044 Free PMC article. No abstract available.
Rhythmic IL-17 production by γδ T cells maintains adipose de novo lipogenesis.
Douglas A, Stevens B, Rendas M, Kane H, Lynch E, Kunkemoeller B, Wessendorf-Rodriguez K, Day EA, Sutton C, Brennan M, O'Brien K, Kohlgruber AC, Prendeville H, Garza AE, O'Neill LAJ, Mills KHG, Metallo CM, Veiga-Fernandes H, Lynch L. Douglas A, et al. Among authors: prendeville h. Nature. 2024 Dec;636(8041):206-214. doi: 10.1038/s41586-024-08131-3. Epub 2024 Oct 30. Nature. 2024. PMID: 39478228 Free PMC article.
Recognition of yeast β-glucan particles triggers immunometabolic signaling required for trained immunity.
Horneck Johnston CJH, Ledwith AE, Lundahl MLE, Charles-Messance H, Hackett EE, O'Shaughnessy SD, Clegg J, Prendeville H, McGrath JP, Walsh AM, Case S, Austen Byrne H, Gautam P, Dempsey E, Corr SC, Sheedy FJ. Horneck Johnston CJH, et al. Among authors: prendeville h. iScience. 2024 Jan 26;27(3):109030. doi: 10.1016/j.isci.2024.109030. eCollection 2024 Mar 15. iScience. 2024. PMID: 38361630 Free PMC article.
23 results