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Page 1
Splicing is an alternate oncogenic pathway activation mechanism in glioma.
Siddaway R, Milos S, Vadivel AKA, Dobson THW, Swaminathan J, Ryall S, Pajovic S, Patel PG, Nazarian J, Becher O, Brudno M, Ramani A, Gopalakrishnan V, Hawkins C. Siddaway R, et al. Among authors: gopalakrishnan v. Nat Commun. 2022 Jan 31;13(1):588. doi: 10.1038/s41467-022-28253-4. Nat Commun. 2022. PMID: 35102191 Free PMC article.
Regulation of USP37 Expression by REST-Associated G9a-Dependent Histone Methylation.
Dobson THW, Hatcher RJ, Swaminathan J, Das CM, Shaik S, Tao RH, Milite C, Castellano S, Taylor PH, Sbardella G, Gopalakrishnan V. Dobson THW, et al. Among authors: gopalakrishnan v. Mol Cancer Res. 2017 Aug;15(8):1073-1084. doi: 10.1158/1541-7786.MCR-16-0424. Epub 2017 May 8. Mol Cancer Res. 2017. PMID: 28483947 Free PMC article.
REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature.
Shaik S, Kennis B, Maegawa S, Schadler K, Yanwen Y, Callegari K, Lulla RR, Goldman S, Nazarian J, Rajaram V, Fangusaro J, Gopalakrishnan V. Shaik S, et al. Among authors: gopalakrishnan v. Oncotarget. 2017 Dec 28;9(4):5233-5250. doi: 10.18632/oncotarget.23750. eCollection 2018 Jan 12. Oncotarget. 2017. PMID: 29435175 Free PMC article.
Preclinical Models of Pediatric Brain Tumors-Forging Ahead.
Dobson THW, Gopalakrishnan V. Dobson THW, et al. Among authors: gopalakrishnan v. Bioengineering (Basel). 2018 Oct 2;5(4):81. doi: 10.3390/bioengineering5040081. Bioengineering (Basel). 2018. PMID: 30279402 Free PMC article. Review.
Transcriptional repressor REST drives lineage stage-specific chromatin compaction at Ptch1 and increases AKT activation in a mouse model of medulloblastoma.
Dobson THW, Tao RH, Swaminathan J, Maegawa S, Shaik S, Bravo-Alegria J, Sharma A, Kennis B, Yang Y, Callegari K, Haltom AR, Taylor P, Kogiso M, Qi L, Khatua S, Goldman S, Lulla RR, Fangusaro J, MacDonald TJ, Li XN, Hawkins C, Rajaram V, Gopalakrishnan V. Dobson THW, et al. Among authors: gopalakrishnan v. Sci Signal. 2019 Jan 22;12(565):eaan8680. doi: 10.1126/scisignal.aan8680. Sci Signal. 2019. PMID: 30670636 Free PMC article.
Pharmacologic inhibition of lysine-specific demethylase 1 as a therapeutic and immune-sensitization strategy in pediatric high-grade glioma.
Bailey CP, Figueroa M, Gangadharan A, Yang Y, Romero MM, Kennis BA, Yadavilli S, Henry V, Collier T, Monje M, Lee DA, Wang L, Nazarian J, Gopalakrishnan V, Zaky W, Becher OJ, Chandra J. Bailey CP, et al. Among authors: gopalakrishnan v. Neuro Oncol. 2020 Sep 29;22(9):1302-1314. doi: 10.1093/neuonc/noaa058. Neuro Oncol. 2020. PMID: 32166329 Free PMC article.
REST promotes ETS1-dependent vascular growth in medulloblastoma.
Shaik S, Maegawa S, Haltom AR, Wang F, Xiao X, Dobson T, Sharma A, Yang Y, Swaminathan J, Kundra V, Li XN, Schadler K, Harmanci A, Xu L, Gopalakrishnan V. Shaik S, et al. Among authors: gopalakrishnan v. Mol Oncol. 2021 May;15(5):1486-1506. doi: 10.1002/1878-0261.12903. Epub 2021 Feb 7. Mol Oncol. 2021. PMID: 33469989 Free PMC article.
393 results