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A Rabbit Model to Study Antibiotic Penetration at the Site of Infection for Nontuberculous Mycobacterial Lung Disease: Macrolide Case Study.
Kaya F, Ernest JP, LoMauro K, Gengenbacher M, Madani A, Aragaw WW, Zimmerman MD, Sarathy JP, Alvarez N, Daudelin I, Wang H, Lanni F, Weiner DM, Via LE, Barry CE 3rd, Olivier KN, Dick T, Podell BK, Savic RM, Dartois V. Kaya F, et al. Among authors: ernest jp. Antimicrob Agents Chemother. 2022 Mar 15;66(3):e0221221. doi: 10.1128/aac.02212-21. Epub 2022 Jan 31. Antimicrob Agents Chemother. 2022. PMID: 35099272 Free PMC article.
Pharmacometrics in tuberculosis: progress and opportunities.
Wilkins JJ, Svensson EM, Ernest JP, Savic RM, Simonsson USH, McIlleron H. Wilkins JJ, et al. Among authors: ernest jp. Int J Antimicrob Agents. 2022 Sep;60(3):106620. doi: 10.1016/j.ijantimicag.2022.106620. Epub 2022 Jun 17. Int J Antimicrob Agents. 2022. PMID: 35724859 Free article. Review.
Dose optimization of TBI-223 for enhanced therapeutic benefit compared to linezolid in antituberculosis regimen.
Strydom N, Ernest JP, Imperial M, Solans BP, Wang Q, Tasneen R, Tyagi S, Soni H, Garcia A, Bigelow K, Gengenbacher M, Zimmerman M, Xie M, Sarathy JP, Yang TJ, Dartois V, Nuermberger EL, Savic RM. Strydom N, et al. Among authors: ernest jp. Nat Commun. 2024 Aug 25;15(1):7311. doi: 10.1038/s41467-024-50781-4. Nat Commun. 2024. PMID: 39181887 Free PMC article. Clinical Trial.
Comparative Efficacy of Rifapentine Alone and in Combination with Isoniazid for Latent Tuberculosis Infection: a Translational Pharmacokinetic-Pharmacodynamic Modeling Study.
Radtke KK, Ernest JP, Zhang N, Ammerman NC, Nuermberger E, Belknap R, Boyd R, Sterling TR, Savic RM. Radtke KK, et al. Among authors: ernest jp. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0170521. doi: 10.1128/AAC.01705-21. Epub 2021 Oct 4. Antimicrob Agents Chemother. 2021. PMID: 34606336 Free PMC article.
Lung microenvironments harbor Mycobacterium tuberculosis phenotypes with distinct treatment responses.
Walter ND, Ernest JP, Dide-Agossou C, Bauman AA, Ramey ME, Rossmassler K, Massoudi LM, Pauly S, Al Mubarak R, Voskuil MI, Kaya F, Sarathy JP, Zimmerman MD, Dartois V, Podell BK, Savic RM, Robertson GT. Walter ND, et al. Among authors: ernest jp. Antimicrob Agents Chemother. 2023 Sep 19;67(9):e0028423. doi: 10.1128/aac.00284-23. Epub 2023 Aug 11. Antimicrob Agents Chemother. 2023. PMID: 37565762 Free PMC article.
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