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Page 1
Parallel evolution of a splicing program controlling neuronal excitability in flies and mammals.
Torres-Méndez A, Pop S, Bonnal S, Almudi I, Avola A, Roberts RJV, Paolantoni C, Alcaina-Caro A, Martín-Anduaga A, Haussmann IU, Morin V, Casares F, Soller M, Kadener S, Roignant JY, Prieto-Godino L, Irimia M. Torres-Méndez A, et al. Among authors: roignant jy. Sci Adv. 2022 Jan 28;8(4):eabk0445. doi: 10.1126/sciadv.abk0445. Epub 2022 Jan 28. Sci Adv. 2022. PMID: 35089784 Free PMC article.
Experience with German Research Consortia in the Field of Chemical Biology of Native Nucleic Acid Modifications.
Helm M, Bohnsack MT, Carell T, Dalpke A, Entian KD, Ehrenhofer-Murray A, Ficner R, Hammann C, Höbartner C, Jäschke A, Jeltsch A, Kaiser S, Klassen R, Leidel SA, Marx A, Mörl M, Meier JC, Meister G, Rentmeister A, Rodnina M, Roignant JY, Schaffrath R, Stadler P, Stafforst T. Helm M, et al. Among authors: roignant jy. ACS Chem Biol. 2023 Dec 15;18(12):2441-2449. doi: 10.1021/acschembio.3c00586. Epub 2023 Nov 14. ACS Chem Biol. 2023. PMID: 37962075 Review.
Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d.
Knuckles P, Lence T, Haussmann IU, Jacob D, Kreim N, Carl SH, Masiello I, Hares T, Villaseñor R, Hess D, Andrade-Navarro MA, Biggiogera M, Helm M, Soller M, Bühler M, Roignant JY. Knuckles P, et al. Among authors: roignant jy. Genes Dev. 2018 Mar 1;32(5-6):415-429. doi: 10.1101/gad.309146.117. Epub 2018 Mar 13. Genes Dev. 2018. PMID: 29535189 Free PMC article.
Mechanistic insights into m6A RNA enzymes.
Lence T, Paolantoni C, Worpenberg L, Roignant JY. Lence T, et al. Among authors: roignant jy. Biochim Biophys Acta Gene Regul Mech. 2019 Mar;1862(3):222-229. doi: 10.1016/j.bbagrm.2018.10.014. Epub 2018 Nov 3. Biochim Biophys Acta Gene Regul Mech. 2019. PMID: 30395944 Review.
Ythdf is a N6-methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila.
Worpenberg L, Paolantoni C, Longhi S, Mulorz MM, Lence T, Wessels HH, Dassi E, Aiello G, Sutandy FXR, Scheibe M, Edupuganti RR, Busch A, Möckel MM, Vermeulen M, Butter F, König J, Notarangelo M, Ohler U, Dieterich C, Quattrone A, Soldano A, Roignant JY. Worpenberg L, et al. Among authors: roignant jy. EMBO J. 2021 Feb 15;40(4):e104975. doi: 10.15252/embj.2020104975. Epub 2021 Jan 11. EMBO J. 2021. PMID: 33428246 Free PMC article.
Hakai is required for stabilization of core components of the m6A mRNA methylation machinery.
Bawankar P, Lence T, Paolantoni C, Haussmann IU, Kazlauskiene M, Jacob D, Heidelberger JB, Richter FM, Nallasivan MP, Morin V, Kreim N, Beli P, Helm M, Jinek M, Soller M, Roignant JY. Bawankar P, et al. Among authors: roignant jy. Nat Commun. 2021 Jun 18;12(1):3778. doi: 10.1038/s41467-021-23892-5. Nat Commun. 2021. PMID: 34145251 Free PMC article.
49 results