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Skin codelivery of contact sensitizers and neurokinin-1 receptor antagonists integrated in microneedle arrays suppresses allergic contact dermatitis.
Bandyopadhyay M, Morelli AE, Balmert SC, Ward NL, Erdos G, Sumpter TL, Korkmaz E, Kaplan DH, Oberbarnscheidt MH, Tkacheva O, Shufesky WJ, Falo LD Jr, Larregina AT. Bandyopadhyay M, et al. Among authors: sumpter tl. J Allergy Clin Immunol. 2022 Jul;150(1):114-130. doi: 10.1016/j.jaci.2021.12.794. Epub 2022 Jan 24. J Allergy Clin Immunol. 2022. PMID: 35085664 Free PMC article.
Neurokinin-1 receptor agonists bias therapeutic dendritic cells to induce type 1 immunity by licensing host dendritic cells to produce IL-12.
Janelsins BM, Sumpter TL, Tkacheva OA, Rojas-Canales DM, Erdos G, Mathers AR, Shufesky WJ, Storkus WJ, Falo LD Jr, Morelli AE, Larregina AT. Janelsins BM, et al. Among authors: sumpter tl. Blood. 2013 Apr 11;121(15):2923-33. doi: 10.1182/blood-2012-07-446054. Epub 2013 Jan 30. Blood. 2013. PMID: 23365459 Free PMC article.
"Toll"-erance in the skin.
Sumpter TL, Falo LD Jr. Sumpter TL, et al. Immunity. 2014 Nov 20;41(5):677-9. doi: 10.1016/j.immuni.2014.11.003. Epub 2014 Nov 20. Immunity. 2014. PMID: 25517608 Free article.
Nonpeptidergic neurons suppress mast cells via glutamate to maintain skin homeostasis.
Zhang S, Edwards TN, Chaudhri VK, Wu J, Cohen JA, Hirai T, Rittenhouse N, Schmitz EG, Zhou PY, McNeil BD, Yang Y, Koerber HR, Sumpter TL, Poholek AC, Davis BM, Albers KM, Singh H, Kaplan DH. Zhang S, et al. Among authors: sumpter tl. Cell. 2021 Apr 15;184(8):2151-2166.e16. doi: 10.1016/j.cell.2021.03.002. Epub 2021 Mar 24. Cell. 2021. PMID: 33765440 Free PMC article.
49 results