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High-dose rifampin improves bactericidal activity without increased intracerebral inflammation in animal models of tuberculous meningitis.
Ruiz-Bedoya CA, Mota F, Tucker EW, Mahmud FJ, Reyes-Mantilla MI, Erice C, Bahr M, Flavahan K, de Jesus P, Kim J, Foss CA, Peloquin CA, Hammoud DA, Ordonez AA, Pardo CA, Jain SK. Ruiz-Bedoya CA, et al. Among authors: kim j. J Clin Invest. 2022 Mar 15;132(6):e155851. doi: 10.1172/JCI155851. J Clin Invest. 2022. PMID: 35085105 Free PMC article.
Sulforaphane exhibits antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses in vitro and in mice.
Ordonez AA, Bullen CK, Villabona-Rueda AF, Thompson EA, Turner ML, Merino VF, Yan Y, Kim J, Davis SL, Komm O, Powell JD, D'Alessio FR, Yolken RH, Jain SK, Jones-Brando L. Ordonez AA, et al. Among authors: kim j. Commun Biol. 2022 Mar 18;5(1):242. doi: 10.1038/s42003-022-03189-z. Commun Biol. 2022. PMID: 35304580 Free PMC article.
Dynamic 18F-Pretomanid PET imaging in animal models of TB meningitis and human studies.
Mota F, Ruiz-Bedoya CA, Tucker EW, Holt DP, De Jesus P, Lodge MA, Erice C, Chen X, Bahr M, Flavahan K, Kim J, Brosnan MK, Ordonez AA, Peloquin CA, Dannals RF, Jain SK. Mota F, et al. Among authors: kim j. Nat Commun. 2022 Dec 29;13(1):7974. doi: 10.1038/s41467-022-35730-3. Nat Commun. 2022. PMID: 36581633 Free PMC article.
Linezolid does not improve bactericidal activity of rifampin-containing first-line regimens in animal models of TB meningitis.
Tucker EW, Ruiz-Bedoya CA, Mota F, Erice C, Kim J, de Jesus P, Jahdav R, Bahr M, Flavahan K, Chen X, Peloquin CA, Freundlich JS, Jain SK. Tucker EW, et al. Among authors: kim j. Int J Antimicrob Agents. 2024 Jan;63(1):107048. doi: 10.1016/j.ijantimicag.2023.107048. Epub 2023 Dec 5. Int J Antimicrob Agents. 2024. PMID: 38061419 Free PMC article.
135,761 results
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