Chen D - Search Results

1

TRIP13, identified as a hub gene of tumor progression, is the target of microRNA-4693-5p and a potential therapeutic target for colorectal cancer.

Chen Y, Chen D, Qin Y, Qiu C, Zhou Y, Dai M, Li L, Sun Q, Jiang Y. Chen Y, et al. Among authors: chen d. Cell Death Discov. 2022 Jan 24;8(1):35. doi: 10.1038/s41420-022-00824-w. Cell Death Discov. 2022. PMID: 35075117 Free PMC article.

2

BGN and COL11A1 Regulatory Network Analysis in Colorectal Cancer (CRC) Reveals That BGN Influences CRC Cell Biological Functions and Interacts with miR-6828-5p.

Chen D, Qin Y, Dai M, Li L, Liu H, Zhou Y, Qiu C, Chen Y, Jiang Y. Chen D, et al. Among authors: chen y. Cancer Manag Res. 2020 Dec 22;12:13051-13069. doi: 10.2147/CMAR.S277261. eCollection 2020. Cancer Manag Res. 2020. PMID: 33376399 Free PMC article.

3

Targeting Hsp90 with FS-108 circumvents gefitinib resistance in EGFR mutant non-small cell lung cancer cells.

Wang YQ, Shen AJ, Sun JY, Wang X, Liu HC, Zhang MM, Chen DQ, Xiong B, Shen JK, Geng MY, Zheng M, Ding J. Wang YQ, et al. Acta Pharmacol Sin. 2016 Dec;37(12):1587-1596. doi: 10.1038/aps.2016.85. Epub 2016 Sep 12. Acta Pharmacol Sin. 2016. PMID: 27616574 Free PMC article.

4

A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction.

Damaneh MS, Hu JP, Huan XJ, Song SS, Tian CQ, Chen DQ, Meng T, Chen YL, Shen JK, Xiong B, Miao ZH, Wang YQ. Damaneh MS, et al. Invest New Drugs. 2020 Jun;38(3):700-713. doi: 10.1007/s10637-019-00818-z. Epub 2019 Jul 3. Invest New Drugs. 2020. PMID: 31267379

5

Tetrahydroisoquinolines as novel histone deacetylase inhibitors for treatment of cancer.

Chen D, Shen A, Fang G, Liu H, Zhang M, Tang S, Xiong B, Ma L, Geng M, Shen J. Chen D, et al. Acta Pharm Sin B. 2016 Jan;6(1):93-9. doi: 10.1016/j.apsb.2015.11.002. Epub 2016 Jan 7. Acta Pharm Sin B. 2016. PMID: 26904403 Free PMC article.

6

Discovery of a new series of imidazo[1,2-a]pyridine compounds as selective c-Met inhibitors.

Liu TC, Peng X, Ma YC, Ji YC, Chen DQ, Zheng MY, Zhao DM, Cheng MS, Geng MY, Shen JK, Ai J, Xiong B. Liu TC, et al. Acta Pharmacol Sin. 2016 May;37(5):698-707. doi: 10.1038/aps.2016.11. Epub 2016 Apr 4. Acta Pharmacol Sin. 2016. PMID: 27041462 Free PMC article.

7

Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors.

Chen D, Shen A, Li J, Shi F, Chen W, Ren J, Liu H, Xu Y, Wang X, Yang X, Sun Y, Yang M, He J, Wang Y, Zhang L, Huang M, Geng M, Xiong B, Shen J. Chen D, et al. Among authors: chen w. Eur J Med Chem. 2014 Nov 24;87:765-81. doi: 10.1016/j.ejmech.2014.09.065. Epub 2014 Sep 22. Eur J Med Chem. 2014. PMID: 25313505

8

Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy.

Zhang Z, Guo Z, Xu X, Cao D, Yang H, Li Y, Shi Q, Du Z, Guo X, Wang X, Chen D, Zhang Y, Chen L, Zhou K, Li J, Geng M, Huang X, Xiong B. Zhang Z, et al. Among authors: chen l, chen d. J Med Chem. 2021 Nov 25;64(22):16650-16674. doi: 10.1021/acs.jmedchem.1c01308. Epub 2021 Nov 15. J Med Chem. 2021. PMID: 34781683

9

Remodeling tumor-associated macrophage for anti-cancer effects by rational design of irreversible inhibition of mitogen-activated protein kinase-activated protein kinase 2.

Wang D, Sun D, Wang X, Peng X, Ji Y, Tang L, He Q, Chen D, Yang Y, Zhou X, Xiong B, Ai J. Wang D, et al. Among authors: chen d. MedComm (2020). 2024 Jul 10;5(7):e634. doi: 10.1002/mco2.634. eCollection 2024 Jul. MedComm (2020). 2024. PMID: 38988492 Free PMC article.

10

Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma.

Wang Q, Dai Y, Ji Y, Shi H, Guo Z, Chen D, Chen Y, Peng X, Gao Y, Wang X, Chen L, Jiang Y, Geng M, Shen J, Ai J, Xiong B. Wang Q, et al. Among authors: chen l, chen d, chen y. Eur J Med Chem. 2019 Feb 1;163:671-689. doi: 10.1016/j.ejmech.2018.12.015. Epub 2018 Dec 7. Eur J Med Chem. 2019. PMID: 30572178

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