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21 results

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Page 1
Atazanavir Is a Competitive Inhibitor of SARS-CoV-2 Mpro, Impairing Variants Replication In Vitro and In Vivo.
Chaves OA, Sacramento CQ, Ferreira AC, Mattos M, Fintelman-Rodrigues N, Temerozo JR, Vazquez L, Pinto DP, da Silveira GPE, da Fonseca LB, Pereira HM, Carlos AS, d'Avila JC, Viola JPB, Monteiro RQ, Bozza PT, Castro-Faria-Neto HC, Souza TML. Chaves OA, et al. Among authors: pinto dp. Pharmaceuticals (Basel). 2021 Dec 24;15(1):21. doi: 10.3390/ph15010021. Pharmaceuticals (Basel). 2021. PMID: 35056078 Free PMC article.
Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin-based combination therapy with primaquine.
Daher A, Aljayyoussi G, Pereira D, Lacerda MVG, Alexandre MAA, Nascimento CT, Alves JC, da Fonseca LB, da Silva DMD, Pinto DP, Rodrigues DF, Silvino ACR, de Sousa TN, de Brito CFA, Ter Kuile FO, Lalloo DG. Daher A, et al. Among authors: pinto dp. Malar J. 2019 Sep 23;18(1):325. doi: 10.1186/s12936-019-2950-4. Malar J. 2019. PMID: 31547827 Free PMC article. Clinical Trial.
Pharmacological profiling of JME-173, a novel mexiletine derivative combining dual anti-inflammatory/anti-spasmodic functions and limited action in Na+ channels.
Pinto DP, Coutinho DS, Carvalho KIM, Ferrero MR, Silva LVD, Silveira GPE, Silva DMD, Araújo JFG, Silva ACA, Pereira HM, Fonseca LBD, Faria RX, Souza MVN, Silva ETD, Santos-Filho OA, Costa JCSD, Amendoeira FC, Martins MA. Pinto DP, et al. Eur J Pharmacol. 2020 Oct 15;885:173367. doi: 10.1016/j.ejphar.2020.173367. Epub 2020 Aug 1. Eur J Pharmacol. 2020. PMID: 32750364
Pharmacokinetics of chloroquine and primaquine in healthy volunteers.
Daher A, Pinto DP, da Fonseca LB, Pereira HM, da Silva DMD, da Silva LSFV, Esteves AL, Soares Medeiros JJ, Mendonça JS. Daher A, et al. Among authors: pinto dp. Malar J. 2022 Jan 8;21(1):16. doi: 10.1186/s12936-021-04035-z. Malar J. 2022. PMID: 34998391 Free PMC article. Clinical Trial.
Development and validation of LC-MS/MS methods for the simultaneous quantification of sofosbuvir and its major metabolite (GS-331007) in blood plasma and cerebrospinal and seminal fluid: Application to a pilot clinical trial with a focus on Zika.
Vilhena LS, de Azevedo da Silva AC, Dias da Silva DM, Pinto DP, Coelho EF, de Araújo JFGM, da Silveira GPE, Pereira HM, da Silva LSFV, Estrela Marins RCE, Bortolini RG, Souza TML, Dos Santos VGV, de Assis Nascimento V, Amendoeira FC, da Fonseca LB. Vilhena LS, et al. Among authors: pinto dp. Biomed Chromatogr. 2023 May;37(5):e5606. doi: 10.1002/bmc.5606. Epub 2023 Mar 5. Biomed Chromatogr. 2023. PMID: 36797051 Clinical Trial.
Newly Proposed Dose of Daclatasvir to Prevent Lethal SARS-CoV-2 Infection in Human Transgenic ACE-2 Mice.
Mattos M, Sacramento CQ, Ferreira AC, Fintelman-Rodrigues N, Pereira-Dutra FS, de Freitas CS, Gesto JSM, Temerozo JR, Silva APDD, Moreira MTG, Silva RSC, Silveira GPE, Pinto DP, Pereira HM, Fonseca LB, Alves Ferreira M, Blanco C, Viola JPB, Bou-Habib DC, Bozza PT, Souza TML. Mattos M, et al. Among authors: pinto dp. Viruses. 2024 Nov 29;16(12):1856. doi: 10.3390/v16121856. Viruses. 2024. PMID: 39772165 Free PMC article.
Preclinical pharmacokinetic evaluation of praziquantel loaded in poly (methyl methacrylate) nanoparticle using a HPLC-MS/MS.
Malhado M, Pinto DP, Silva AC, Silveira GP, Pereira HM, Santos JG Jr, Guilarducci-Ferraz CV, Viçosa AL, Nele M, Fonseca LB, Pinto JC, Calil-Elias S. Malhado M, et al. Among authors: pinto dp, pinto jc. J Pharm Biomed Anal. 2016 Jan 5;117:405-12. doi: 10.1016/j.jpba.2015.09.023. Epub 2015 Sep 25. J Pharm Biomed Anal. 2016. PMID: 26440288
Cynomolgus monkeys are successfully and persistently infected with hepatitis E virus genotype 3 (HEV-3) after long-term immunosuppressive therapy.
Gardinali NR, Guimarães JR, Melgaço JG, Kevorkian YB, Bottino FO, Vieira YR, da Silva AC, Pinto DP, da Fonseca LB, Vilhena LS, Uiechi E, da Silva MC, Moran J, Marchevsky RS, Cruz OG, Otonel RA, Alfieri AA, de Oliveira JM, Gaspar AM, Pinto MA. Gardinali NR, et al. Among authors: pinto dp, pinto ma. PLoS One. 2017 Mar 22;12(3):e0174070. doi: 10.1371/journal.pone.0174070. eCollection 2017. PLoS One. 2017. PMID: 28328941 Free PMC article.
21 results