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Phase 1 clinical trial demonstrated that MUC1 positive metastatic seminal vesicle cancer can be effectively eradicated by modified Anti-MUC1 chimeric antigen receptor transduced T cells.
You F, Jiang L, Zhang B, Lu Q, Zhou Q, Liao X, Wu H, Du K, Zhu Y, Meng H, Gong Z, Zong Y, Huang L, Lu M, Tang J, Li Y, Zhai X, Wang X, Ye S, Chen D, Yuan L, Qi L, Yang L. You F, et al. Among authors: jiang l. Sci China Life Sci. 2016 Apr;59(4):386-97. doi: 10.1007/s11427-016-5024-7. Epub 2016 Mar 7. Sci China Life Sci. 2016. PMID: 26961900 Clinical Trial.
CD7 protein plays a crucial role in T cell infiltration in tumors.
Sheng B, Zhang K, Tian S, Ma R, Li Z, Wu H, Wang T, Jiang L, You F, An G, Meng H, Yang L, Liu X. Sheng B, et al. Among authors: jiang l. Heliyon. 2023 Jun 15;9(6):e16961. doi: 10.1016/j.heliyon.2023.e16961. eCollection 2023 Jun. Heliyon. 2023. PMID: 37416646 Free PMC article.
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