DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser56 to diminish pancreatic β cell function upon overnutrition.
Lu Y, Xu J, Li Y, Wang R, Dai C, Zhang B, Zhang X, Xu L, Tao Y, Han M, Guo R, Wu Q, Wu L, Meng Z, Tan M, Li J.
Lu Y, et al.
Sci Transl Med. 2024 Feb 7;16(733):eade8647. doi: 10.1126/scitranslmed.ade8647. Epub 2024 Feb 7.
Sci Transl Med. 2024.
PMID: 38324636