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Page 1
Multiplex genome editing of mammalian cells for producing recombinant heparin.
Thacker BE, Thorne KJ, Cartwright C, Park J, Glass K, Chea A, Kellman BP, Lewis NE, Wang Z, Di Nardo A, Sharfstein ST, Jeske W, Walenga J, Hogwood J, Gray E, Mulloy B, Esko JD, Glass CA. Thacker BE, et al. Among authors: esko jd. Metab Eng. 2022 Mar;70:155-165. doi: 10.1016/j.ymben.2022.01.002. Epub 2022 Jan 14. Metab Eng. 2022. PMID: 35038554 Free article.
Surfen, a small molecule antagonist of heparan sulfate.
Schuksz M, Fuster MM, Brown JR, Crawford BE, Ditto DP, Lawrence R, Glass CA, Wang L, Tor Y, Esko JD. Schuksz M, et al. Among authors: esko jd. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13075-80. doi: 10.1073/pnas.0805862105. Epub 2008 Aug 25. Proc Natl Acad Sci U S A. 2008. PMID: 18725627 Free PMC article.
Bioengineering murine mastocytoma cells to produce anticoagulant heparin.
Gasimli L, Glass CA, Datta P, Yang B, Li G, Gemmill TR, Baik JY, Sharfstein ST, Esko JD, Linhardt RJ. Gasimli L, et al. Among authors: esko jd. Glycobiology. 2014 Mar;24(3):272-80. doi: 10.1093/glycob/cwt108. Epub 2013 Dec 9. Glycobiology. 2014. PMID: 24326668 Free PMC article.
As reported, MST cells produce a highly sulfated HP-like polysaccharide that lacks anticoagulant activity (Montgomery RI, Lidholt K, Flay NW, Liang J, Vertel B, Lindahl U, Esko JD. 1992. Stable heparin-producing cell lines derived from the Furth murine mastocytoma. …
As reported, MST cells produce a highly sulfated HP-like polysaccharide that lacks anticoagulant activity (Montgomery RI, Lidholt K, Flay NW …
Targeting heparin and heparan sulfate protein interactions.
Weiss RJ, Esko JD, Tor Y. Weiss RJ, et al. Among authors: esko jd. Org Biomol Chem. 2017 Jul 21;15(27):5656-5668. doi: 10.1039/c7ob01058c. Epub 2017 Jun 27. Org Biomol Chem. 2017. PMID: 28653068 Free PMC article. Review.
341 results