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Page 1
eNAMPT neutralization reduces preclinical ARDS severity via rectified NFkB and Akt/mTORC2 signaling.
Bermudez T, Sammani S, Song JH, Hernon VR, Kempf CL, Garcia AN, Burt J, Hufford M, Camp SM, Cress AE, Desai AA, Natarajan V, Jacobson JR, Dudek SM, Cancio LC, Alvarez J, Rafikov R, Li Y, Zhang DD, Casanova NG, Bime C, Garcia JGN. Bermudez T, et al. Among authors: hernon vr. Sci Rep. 2022 Jan 13;12(1):696. doi: 10.1038/s41598-021-04444-9. Sci Rep. 2022. PMID: 35027578 Free PMC article.
Involvement of eNAMPT/TLR4 signaling in murine radiation pneumonitis: protection by eNAMPT neutralization.
Garcia AN, Casanova NG, Valera DG, Sun X, Song JH, Kempf CL, Moreno-Vinasco L, Burns K, Bermudez T, Valdez M, Cuellar G, Gregory T, Oita RC, Hernon VR, Barber C, Camp SM, Martin D, Liu Z, Bime C, Sammani S, Cress AE, Garcia JG. Garcia AN, et al. Among authors: hernon vr. Transl Res. 2022 Jan;239:44-57. doi: 10.1016/j.trsl.2021.06.002. Epub 2021 Jun 15. Transl Res. 2022. PMID: 34139379 Free PMC article.
Endothelial eNAMPT drives EndMT and preclinical PH: rescue by an eNAMPT-neutralizing mAb.
Ahmed M, Zaghloul N, Zimmerman P, Casanova NG, Sun X, Song JH, Hernon VR, Sammani S, Rischard F, Rafikova O, Rafikov R, Makino A, Kempf CL, Camp SM, Wang J, Desai AA, Lussier Y, Yuan JX, Garcia JGN. Ahmed M, et al. Among authors: hernon vr. Pulm Circ. 2021 Nov 12;11(4):20458940211059712. doi: 10.1177/20458940211059712. eCollection 2021 Oct-Dec. Pulm Circ. 2021. PMID: 34790349 Free PMC article.
eNAMPT Is a Novel Damage-associated Molecular Pattern Protein That Contributes to the Severity of Radiation-induced Lung Fibrosis.
Garcia AN, Casanova NG, Kempf CL, Bermudez T, Valera DG, Song JH, Sun X, Cai H, Moreno-Vinasco L, Gregory T, Oita RC, Hernon VR, Camp SM, Rogers C, Kyubwa EM, Menon N, Axtelle J, Rappaport J, Bime C, Sammani S, Cress AE, Garcia JGN. Garcia AN, et al. Among authors: hernon vr. Am J Respir Cell Mol Biol. 2022 May;66(5):497-509. doi: 10.1165/rcmb.2021-0357OC. Am J Respir Cell Mol Biol. 2022. PMID: 35167418 Free PMC article.
The eNAMPT/TLR4 inflammatory cascade drives the severity of intra-amniotic inflammation in pregnancy and predicts infant outcomes.
Ahmed M, Casanova NG, Zaghloul N, Gupta A, Rodriguez M, Robbins IR, Kempf CL, Sun X, Song JH, Hernon VR, Sammani S, Camp SM, Moreira A, Hsu CD, Garcia JGN. Ahmed M, et al. Among authors: hernon vr. Front Physiol. 2023 Jun 20;14:1129413. doi: 10.3389/fphys.2023.1129413. eCollection 2023. Front Physiol. 2023. PMID: 37415908 Free PMC article.