Zhao Y - Search Results

1

Main active components of Si-Miao-Yong-An decoction (SMYAD) attenuate autophagy and apoptosis via the PDE5A-AKT and TLR4-NOX4 pathways in isoproterenol (ISO)-induced heart failure models.

Liao M, Xie Q, Zhao Y, Yang C, Lin C, Wang G, Liu B, Zhu L. Liao M, et al. Among authors: zhao y. Pharmacol Res. 2022 Feb;176:106077. doi: 10.1016/j.phrs.2022.106077. Epub 2022 Jan 10. Pharmacol Res. 2022. PMID: 35026404

2

Dissection of mechanisms of Chinese medicinal formula Si-Miao-Yong-an decoction protects against cardiac hypertrophy and fibrosis in isoprenaline-induced heart failure.

Zhao Y, Jiang Y, Chen Y, Zhang F, Zhang X, Zhu L, Yao X. Zhao Y, et al. J Ethnopharmacol. 2020 Feb 10;248:112050. doi: 10.1016/j.jep.2019.112050. Epub 2019 Jun 29. J Ethnopharmacol. 2020. PMID: 31265887

3

Si-Miao-Yong-An Decoction attenuates isoprenaline-induced myocardial fibrosis in AMPK-driven Akt/mTOR and TGF-β/SMAD3 pathways.

Zhao Y, Sun D, Chen Y, Zhan K, Meng Q, Zhang X, Zhu L, Yao X. Zhao Y, et al. Biomed Pharmacother. 2020 Oct;130:110522. doi: 10.1016/j.biopha.2020.110522. Epub 2020 Jul 28. Biomed Pharmacother. 2020. PMID: 32736236 Free article.

4

Si-Miao-Yong-An Decoction Maintains the Cardiac Function and Protects Cardiomyocytes from Myocardial Ischemia and Reperfusion Injury.

Cui W, Xin S, Zhu L, Wang M, Hao Y, Zhao Y, Li Y, Hou Y. Cui W, et al. Among authors: zhao y. Evid Based Complement Alternat Med. 2021 Jul 26;2021:8968464. doi: 10.1155/2021/8968464. eCollection 2021. Evid Based Complement Alternat Med. 2021. PMID: 34367308 Free PMC article.

5

Characterization of HJ-PI01 as a novel Pim-2 inhibitor that induces apoptosis and autophagic cell death in triple-negative human breast cancer.

Zhao YQ, Yin YQ, Liu J, Wang GH, Huang J, Zhu LJ, Wang JH. Zhao YQ, et al. Acta Pharmacol Sin. 2016 Sep;37(9):1237-50. doi: 10.1038/aps.2016.60. Epub 2016 Jul 11. Acta Pharmacol Sin. 2016. PMID: 27397540 Free PMC article.

6

A natural product from Cannabis sativa subsp. sativa inhibits homeodomain-interacting protein kinase 2 (HIPK2), attenuating MPP⁺-induced apoptosis in human neuroblastoma SH-SY5Y cells.

Wang G, Zhu L, Zhao Y, Gao S, Sun D, Yuan J, Huang Y, Zhang X, Yao X. Wang G, et al. Among authors: zhao y. Bioorg Chem. 2017 Jun;72:64-73. doi: 10.1016/j.bioorg.2017.03.011. Epub 2017 Mar 30. Bioorg Chem. 2017. PMID: 28366826

7

Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer.

Ouyang L, Zhang L, Liu J, Fu L, Yao D, Zhao Y, Zhang S, Wang G, He G, Liu B. Ouyang L, et al. Among authors: zhao y. J Med Chem. 2017 Dec 28;60(24):9990-10012. doi: 10.1021/acs.jmedchem.7b00275. Epub 2017 Dec 7. J Med Chem. 2017. PMID: 29172540

8

Design, synthesis and structure-activity relationship of a focused library of β-phenylalanine derivatives as novel eEF2K inhibitors with apoptosis-inducing mechanisms in breast cancer.

Guo Y, Zhao Y, Wang G, Chen Y, Jiang Y, Ouyang L, Liu B. Guo Y, et al. Among authors: zhao y. Eur J Med Chem. 2018 Jan 1;143:402-418. doi: 10.1016/j.ejmech.2017.11.065. Epub 2017 Dec 1. Eur J Med Chem. 2018. PMID: 29202403

9

Small-Molecule Activator of UNC-51-Like Kinase 1 (ULK1) That Induces Cytoprotective Autophagy for Parkinson's Disease Treatment.

Ouyang L, Zhang L, Zhang S, Yao D, Zhao Y, Wang G, Fu L, Lei P, Liu B. Ouyang L, et al. Among authors: zhao y. J Med Chem. 2018 Apr 12;61(7):2776-2792. doi: 10.1021/acs.jmedchem.7b01575. Epub 2018 Mar 29. J Med Chem. 2018. PMID: 29561612

10

Diarylheptanoid: A privileged structure in drug discovery.

Sun DJ, Zhu LJ, Zhao YQ, Zhen YQ, Zhang L, Lin CC, Chen LX. Sun DJ, et al. Fitoterapia. 2020 Apr;142:104490. doi: 10.1016/j.fitote.2020.104490. Epub 2020 Feb 1. Fitoterapia. 2020. PMID: 32017968 Review.

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