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Page 1
Epigenetic scores for the circulating proteome as tools for disease prediction.
Gadd DA, Hillary RF, McCartney DL, Zaghlool SB, Stevenson AJ, Cheng Y, Fawns-Ritchie C, Nangle C, Campbell A, Flaig R, Harris SE, Walker RM, Shi L, Tucker-Drob EM, Gieger C, Peters A, Waldenberger M, Graumann J, McRae AF, Deary IJ, Porteous DJ, Hayward C, Visscher PM, Cox SR, Evans KL, McIntosh AM, Suhre K, Marioni RE. Gadd DA, et al. Among authors: graumann j. Elife. 2022 Jan 13;11:e71802. doi: 10.7554/eLife.71802. Elife. 2022. PMID: 35023833 Free PMC article.
Reciprocal crosstalk between Th17 and mesothelial cells promotes metastasis-associated adhesion of ovarian cancer cells.
Neuhaus F, Lieber S, Shinkevich V, Steitz AM, Raifer H, Roth K, Finkernagel F, Worzfeld T, Burchert A, Keber C, Nist A, Stiewe T, Reinartz S, Beutgen VM, Graumann J, Pauck K, Garn H, Gaida M, Müller R, Huber M. Neuhaus F, et al. Among authors: graumann j. Clin Transl Med. 2024 Apr;14(4):e1604. doi: 10.1002/ctm2.1604. Clin Transl Med. 2024. PMID: 38566518 Free PMC article.
Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence.
Lluch A, Latorre J, Serena-Maione A, Espadas I, Caballano-Infantes E, Moreno-Navarrete JM, Oliveras-Cañellas N, Ricart W, Malagón MM, Martin-Montalvo A, Birchmeier W, Szymanski W, Graumann J, Gómez-Serrano M, Sommariva E, Fernández-Real JM, Ortega FJ. Lluch A, et al. Among authors: graumann j. Nat Commun. 2023 Aug 22;14(1):5106. doi: 10.1038/s41467-023-40596-0. Nat Commun. 2023. PMID: 37607954 Free PMC article.
BAG6 restricts pancreatic cancer progression by suppressing the release of IL33-presenting extracellular vesicles and the activation of mast cells.
Alashkar Alhamwe B, Ponath V, Alhamdan F, Dörsam B, Landwehr C, Linder M, Pauck K, Miethe S, Garn H, Finkernagel F, Brichkina A, Lauth M, Tiwari DK, Buchholz M, Bachurski D, Elmshäuser S, Nist A, Stiewe T, Pogge von Strandmann L, Szymański W, Beutgen V, Graumann J, Teply-Szymanski J, Keber C, Denkert C, Jacob R, Preußer C, Pogge von Strandmann E. Alashkar Alhamwe B, et al. Among authors: graumann j. Cell Mol Immunol. 2024 Aug;21(8):918-931. doi: 10.1038/s41423-024-01195-1. Epub 2024 Jun 28. Cell Mol Immunol. 2024. PMID: 38942797 Free PMC article.
Connecting genetic risk to disease end points through the human blood plasma proteome.
Suhre K, Arnold M, Bhagwat AM, Cotton RJ, Engelke R, Raffler J, Sarwath H, Thareja G, Wahl A, DeLisle RK, Gold L, Pezer M, Lauc G, El-Din Selim MA, Mook-Kanamori DO, Al-Dous EK, Mohamoud YA, Malek J, Strauch K, Grallert H, Peters A, Kastenmüller G, Gieger C, Graumann J. Suhre K, et al. Among authors: graumann j. Nat Commun. 2017 Feb 27;8:14357. doi: 10.1038/ncomms14357. Nat Commun. 2017. PMID: 28240269 Free PMC article.
Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation.
Zaghlool SB, Mook-Kanamori DO, Kader S, Stephan N, Halama A, Engelke R, Sarwath H, Al-Dous EK, Mohamoud YA, Roemisch-Margl W, Adamski J, Kastenmüller G, Friedrich N, Visconti A, Tsai PC, Spector T, Bell JT, Falchi M, Wahl A, Waldenberger M, Peters A, Gieger C, Pezer M, Lauc G, Graumann J, Malek JA, Suhre K. Zaghlool SB, et al. Among authors: graumann j. Hum Mol Genet. 2018 Mar 15;27(6):1106-1121. doi: 10.1093/hmg/ddy006. Hum Mol Genet. 2018. PMID: 29325019 Free PMC article.
Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.
Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D. Yao C, et al. Among authors: graumann j. Nat Commun. 2018 Aug 15;9(1):3268. doi: 10.1038/s41467-018-05512-x. Nat Commun. 2018. PMID: 30111768 Free PMC article.
Author Correction: Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.
Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D. Yao C, et al. Among authors: graumann j. Nat Commun. 2018 Sep 18;9(1):3853. doi: 10.1038/s41467-018-06231-z. Nat Commun. 2018. PMID: 30228274 Free PMC article.
118 results