Kwan K - Search Results

1

Broad activation of the Parkin pathway induces synaptic mitochondrial deficits in early tauopathy.

Jeong YY, Han S, Jia N, Zhang M, Sheshadri P, Tammineni P, Cheung J, Nissenbaum M, Baskar SS, Kwan K, Margolis DJ, Jiang P, Kusnecov AW, Cai Q. Jeong YY, et al. Among authors: kwan k. Brain. 2022 Mar 29;145(1):305-323. doi: 10.1093/brain/awab243. Brain. 2022. PMID: 35022692 Free PMC article.

2

SNX-1 and RME-8 oppose the assembly of HGRS-1/ESCRT-0 degradative microdomains on endosomes.

Norris A, Tammineni P, Wang S, Gerdes J, Murr A, Kwan KY, Cai Q, Grant BD. Norris A, et al. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E307-E316. doi: 10.1073/pnas.1612730114. Epub 2017 Jan 4. Proc Natl Acad Sci U S A. 2017. PMID: 28053230 Free PMC article.

3

Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain.

Xu R, Li X, Boreland AJ, Posyton A, Kwan K, Hart RP, Jiang P. Xu R, et al. Among authors: kwan k. Nat Commun. 2020 Mar 27;11(1):1577. doi: 10.1038/s41467-020-15411-9. Nat Commun. 2020. PMID: 32221280 Free PMC article.

4

Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer's disease.

Jin M, Xu R, Wang L, Alam MM, Ma Z, Zhu S, Martini AC, Jadali A, Bernabucci M, Xie P, Kwan KY, Pang ZP, Head E, Liu Y, Hart RP, Jiang P. Jin M, et al. Cell Stem Cell. 2022 Jul 7;29(7):1135-1153.e8. doi: 10.1016/j.stem.2022.06.007. Cell Stem Cell. 2022. PMID: 35803230 Free PMC article.

5

Xrn1 is a deNADding enzyme modulating mitochondrial NAD-capped RNA.

Sharma S, Yang J, Grudzien-Nogalska E, Shivas J, Kwan KY, Kiledjian M. Sharma S, et al. Nat Commun. 2022 Feb 16;13(1):889. doi: 10.1038/s41467-022-28555-7. Nat Commun. 2022. PMID: 35173156 Free PMC article.

6

Heat shock promotes inclusion body formation of mutant huntingtin (mHtt) and alleviates mHtt-induced transcription factor dysfunction.

Chen JY, Parekh M, Seliman H, Bakshinskaya D, Dai W, Kwan K, Chen KY, Liu AYC. Chen JY, et al. Among authors: kwan k. J Biol Chem. 2018 Oct 5;293(40):15581-15593. doi: 10.1074/jbc.RA118.002933. Epub 2018 Aug 24. J Biol Chem. 2018. PMID: 30143534 Free PMC article.

7

shox2 is required for vestibular statoacoustic neuron development.

Laureano AS, Flaherty K, Hinman AM, Jadali A, Nakamura T, Higashijima SI, Sabaawy HE, Kwan KY. Laureano AS, et al. Among authors: kwan ky. Biol Open. 2022 Dec 15;11(12):bio059599. doi: 10.1242/bio.059599. Epub 2022 Dec 21. Biol Open. 2022. PMID: 36594417 Free PMC article.

8

Activation of PI3K signaling prevents aminoglycoside-induced hair cell death in the murine cochlea.

Jadali A, Kwan KY. Jadali A, et al. Biol Open. 2016 Jun 15;5(6):698-708. doi: 10.1242/bio.016758. Biol Open. 2016. PMID: 27142333 Free PMC article.

9

Sensory Neuron-Specific Deletion of TRPA1 Results in Mechanical Cutaneous Sensory Deficits.

Zappia KJ, O'Hara CL, Moehring F, Kwan KY, Stucky CL. Zappia KJ, et al. eNeuro. 2017 Mar 13;4(1):ENEURO.0069-16.2017. doi: 10.1523/ENEURO.0069-16.2017. eCollection 2017 Jan-Feb. eNeuro. 2017. PMID: 28303259 Free PMC article.

10

Activation of CHK1 in Supporting Cells Indirectly Promotes Hair Cell Survival.

Jadali A, Ying YM, Kwan KY. Jadali A, et al. Front Cell Neurosci. 2017 May 18;11:137. doi: 10.3389/fncel.2017.00137. eCollection 2017. Front Cell Neurosci. 2017. PMID: 28572758 Free PMC article.

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