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The chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicity.
Plotegher N, Kumar D, Tessari I, Brucale M, Munari F, Tosatto L, Belluzzi E, Greggio E, Bisaglia M, Capaldi S, Aioanei D, Mammi S, Monaco HL, Samo B, Bubacco L. Plotegher N, et al. Among authors: capaldi s. Hum Mol Genet. 2014 Nov 1;23(21):5615-29. doi: 10.1093/hmg/ddu275. Epub 2014 Jun 3. Hum Mol Genet. 2014. PMID: 24895406
The long variant of human ileal bile acid-binding protein associated with colorectal cancer exhibits sub-cellular localization and lipid binding behaviour distinct from those of the common isoform.
D'Onofrio M, Zanzoni S, Munari F, Monaco HL, Assfalg M, Capaldi S. D'Onofrio M, et al. Among authors: capaldi s. Biochim Biophys Acta Gen Subj. 2017 Sep;1861(9):2315-2324. doi: 10.1016/j.bbagen.2017.07.004. Epub 2017 Jul 6. Biochim Biophys Acta Gen Subj. 2017. PMID: 28689989
Pathophysiological Consequences of Neuronal α-Synuclein Overexpression: Impacts on Ion Homeostasis, Stress Signaling, Mitochondrial Integrity, and Electrical Activity.
Tolö J, Taschenberger G, Leite K, Stahlberg MA, Spehlbrink G, Kues J, Munari F, Capaldi S, Becker S, Zweckstetter M, Dean C, Bähr M, Kügler S. Tolö J, et al. Among authors: capaldi s. Front Mol Neurosci. 2018 Mar 7;11:49. doi: 10.3389/fnmol.2018.00049. eCollection 2018. Front Mol Neurosci. 2018. PMID: 29563864 Free PMC article.
67 results