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The MEK1/2-inhibitor ATR-002 efficiently blocks SARS-CoV-2 propagation and alleviates pro-inflammatory cytokine/chemokine responses.
Schreiber A, Viemann D, Schöning J, Schloer S, Mecate Zambrano A, Brunotte L, Faist A, Schöfbänker M, Hrincius E, Hoffmann H, Hoffmann M, Pöhlmann S, Rescher U, Planz O, Ludwig S. Schreiber A, et al. Among authors: schoning j. Cell Mol Life Sci. 2022 Jan 10;79(1):65. doi: 10.1007/s00018-021-04085-1. Cell Mol Life Sci. 2022. PMID: 35013790 Free PMC article.
Influenza A viruses limit NLRP3-NEK7-complex formation and pyroptosis in human macrophages.
Boal-Carvalho I, Mazel-Sanchez B, Silva F, Garnier L, Yildiz S, Bonifacio JP, Niu C, Williams N, Francois P, Schwerk N, Schöning J, Carlens J, Viemann D, Hugues S, Schmolke M. Boal-Carvalho I, et al. Among authors: schoning j. EMBO Rep. 2020 Dec 3;21(12):e50421. doi: 10.15252/embr.202050421. Epub 2020 Nov 12. EMBO Rep. 2020. PMID: 33180976 Free PMC article.
A clinical protocol for a German birth cohort study of the Maturation of Immunity Against respiratory viral Infections (MIAI).
Hartmann CR, Khan R, Schöning J, Richter M, Willers M, Pirr S, Heckmann J, Dirks J, Morbach H, Konrad M, Fries E, Winkler M, Büchel J, Seidenspinner S, Fischer J, Vollmuth C, Meinhardt M, Marissen J, Schmolke M, Haid S, Pietschmann T, Backes S, Dölken L, Löber U, Keil T, Heuschmann PU, Wöckel A, Sagar, Ulas T, Forslund-Startceva SK, Härtel C, Viemann D. Hartmann CR, et al. Among authors: schoning j. Front Immunol. 2024 Sep 17;15:1443665. doi: 10.3389/fimmu.2024.1443665. eCollection 2024. Front Immunol. 2024. PMID: 39355253 Free PMC article.
S100-alarmin-induced innate immune programming protects newborn infants from sepsis.
Ulas T, Pirr S, Fehlhaber B, Bickes MS, Loof TG, Vogl T, Mellinger L, Heinemann AS, Burgmann J, Schöning J, Schreek S, Pfeifer S, Reuner F, Völlger L, Stanulla M, von Köckritz-Blickwede M, Glander S, Barczyk-Kahlert K, von Kaisenberg CS, Friesenhagen J, Fischer-Riepe L, Zenker S, Schultze JL, Roth J, Viemann D. Ulas T, et al. Among authors: schoning j. Nat Immunol. 2017 Jun;18(6):622-632. doi: 10.1038/ni.3745. Epub 2017 May 1. Nat Immunol. 2017. PMID: 28459433
Microbial exposure drives polyclonal expansion of innate γδ T cells immediately after birth.
Ravens S, Fichtner AS, Willers M, Torkornoo D, Pirr S, Schöning J, Deseke M, Sandrock I, Bubke A, Wilharm A, Dodoo D, Egyir B, Flanagan KL, Steinbrück L, Dickinson P, Ghazal P, Adu B, Viemann D, Prinz I. Ravens S, et al. Among authors: schoning j. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18649-18660. doi: 10.1073/pnas.1922588117. Epub 2020 Jul 20. Proc Natl Acad Sci U S A. 2020. PMID: 32690687 Free PMC article.
S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants.
Willers M, Ulas T, Völlger L, Vogl T, Heinemann AS, Pirr S, Pagel J, Fehlhaber B, Halle O, Schöning J, Schreek S, Löber U, Essex M, Hombach P, Graspeuntner S, Basic M, Bleich A, Cloppenborg-Schmidt K, Künzel S, Jonigk D, Rupp J, Hansen G, Förster R, Baines JF, Härtel C, Schultze JL, Forslund SK, Roth J, Viemann D. Willers M, et al. Among authors: schoning j. Gastroenterology. 2020 Dec;159(6):2130-2145.e5. doi: 10.1053/j.gastro.2020.08.019. Epub 2020 Aug 15. Gastroenterology. 2020. PMID: 32805279 Free article.
γδ T cell profiling in a cohort of preterm infants reveals elevated frequencies of CD83+ γδ T cells in sepsis.
León-Lara X, Fichtner AS, Willers M, Yang T, Schaper K, Riemann L, Schöning J, Harms A, Almeida V, Schimrock A, Janssen A, Ospina-Quintero L, von Kaisenberg C, Förster R, Eberl M, Richter MF, Pirr S, Viemann D, Ravens S. León-Lara X, et al. Among authors: schoning j. J Exp Med. 2024 Jul 1;221(7):e20231987. doi: 10.1084/jem.20231987. Epub 2024 May 16. J Exp Med. 2024. PMID: 38753245 Free PMC article.
Mutations of the gene FNIP1 associated with a syndromic autosomal recessive immunodeficiency with cardiomyopathy and pre-excitation syndrome.
Niehues T, Özgür TT, Bickes M, Waldmann R, Schöning J, Bräsen J, Hagel C, Ballmaier M, Klusmann JH, Niedermayer A, Pannicke U, Enders A, Dückers G, Siepermann K, Hempel J, Schwarz K, Viemann D. Niehues T, et al. Among authors: schoning j. Eur J Immunol. 2020 Jul;50(7):1078-1080. doi: 10.1002/eji.201948504. Epub 2020 Apr 20. Eur J Immunol. 2020. PMID: 32181500 Free article.
Corrigendum: S100-alarmin-induced innate immune programming protects newborn infants from sepsis.
Ulas T, Pirr S, Fehlhaber B, Bickes MS, Loof TG, Vogl T, Mellinger L, Heinemann AS, Burgmann J, Schöning J, Schreek S, Pfeifer S, Reuner F, Völlger L, Stanulla M, von Köckritz-Blickwede M, Glander S, Barczyk-Kahlert K, von Kaisenberg CS, Friesenhagen J, Fischer-Riepe L, Zenker S, Schultze JL, Roth J, Viemann D. Ulas T, et al. Among authors: schoning j. Nat Immunol. 2017 Sep 19;18(10):1173. doi: 10.1038/ni1017-1173b. Nat Immunol. 2017. PMID: 28926540 No abstract available.
41 results