Alam A - Search Results

1

Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment.

Le LTM, Thompson JR, Dang PX, Bhandari J, Alam A. Le LTM, et al. Among authors: alam a. Commun Biol. 2022 Jan 10;5(1):7. doi: 10.1038/s42003-021-02970-w. Commun Biol. 2022. PMID: 35013584 Free PMC article.

2

Structure of the human lipid exporter ABCB4 in a lipid environment.

Olsen JA, Alam A, Kowal J, Stieger B, Locher KP. Olsen JA, et al. Among authors: alam a. Nat Struct Mol Biol. 2020 Jan;27(1):62-70. doi: 10.1038/s41594-019-0354-3. Epub 2019 Dec 23. Nat Struct Mol Biol. 2020. PMID: 31873305 Free article.

3

Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.

Nosol K, Romane K, Irobalieva RN, Alam A, Kowal J, Fujita N, Locher KP. Nosol K, et al. Among authors: alam a. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26245-26253. doi: 10.1073/pnas.2010264117. Epub 2020 Oct 5. Proc Natl Acad Sci U S A. 2020. PMID: 33020312 Free PMC article.

4

A Simple and Straightforward Approach for Generating Small, Stable, Homogeneous, Unilamellar 1-Palmitoyl 2-Oleoyl Phosphatidylcholine (POPC) Bilayer Vesicles.

Gao YG, Le LTM, Alam A, Brown RE. Gao YG, et al. Among authors: alam a. Bio Protoc. 2021 Dec 20;11(24):e4271. doi: 10.21769/BioProtoc.4271. eCollection 2021 Dec 20. Bio Protoc. 2021. PMID: 35087930 Free PMC article.

5

Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.

Le LTM, Thompson JR, Dehghani-Ghahnaviyeh S, Pant S, Dang PX, French JB, Kanikeyo T, Tajkhorshid E, Alam A. Le LTM, et al. Among authors: alam a. EMBO J. 2023 Feb 1;42(3):e111065. doi: 10.15252/embj.2022111065. Epub 2022 Dec 9. EMBO J. 2023. PMID: 36484366 Free PMC article.

6

Structural insight into binding site access and ligand recognition by human ABCB1.

Kurre D, Dang PX, Le LTM, Gadkari VV, Alam A. Kurre D, et al. Among authors: alam a. bioRxiv [Preprint]. 2024 Aug 12:2024.08.12.607598. doi: 10.1101/2024.08.12.607598. bioRxiv. 2024. Update in: EMBO J. 2025 Jan 13. doi: 10.1038/s44318-025-00361-z PMID: 39185192 Free PMC article. Updated. Preprint.

7

Use of Bicelle-Generated Lipid Bilayer Vesicle Nanoparticles for In Vitro Measurement of Lipid Intermembrane Transport.

Gao Y, Le LTM, Alam A, Brown RE. Gao Y, et al. Among authors: alam a. Methods Mol Biol. 2025;2888:201-219. doi: 10.1007/978-1-0716-4318-1_14. Methods Mol Biol. 2025. PMID: 39699733

8

Structural insights into binding-site access and ligand recognition by human ABCB1.

Kurre D, Dang PX, Le LTM, Gadkari VV, Alam A. Kurre D, et al. Among authors: alam a. EMBO J. 2025 Jan 13. doi: 10.1038/s44318-025-00361-z. Online ahead of print. EMBO J. 2025. PMID: 39806099 Free article.

9

Structure and Mechanism of Human ABC Transporters.

Alam A, Locher KP. Alam A, et al. Annu Rev Biophys. 2023 May 9;52:275-300. doi: 10.1146/annurev-biophys-111622-091232. Epub 2023 Feb 3. Annu Rev Biophys. 2023. PMID: 36737602 Free article. Review.

10

Structural insight into substrate and inhibitor discrimination by human P-glycoprotein.

Alam A, Kowal J, Broude E, Roninson I, Locher KP. Alam A, et al. Science. 2019 Feb 15;363(6428):753-756. doi: 10.1126/science.aav7102. Science. 2019. PMID: 30765569 Free PMC article.

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