CBR3 V244M is associated with LVEF reduction in breast cancer patients treated with doxorubicin.
Lang JK, Karthikeyan B, Quiñones-Lombraña A, Blair RH, Early AP, Levine EG, Sharma UC, Blanco JG, O'Connor T.
Lang JK, et al. Among authors: early ap.
Cardiooncology. 2021 May 11;7(1):17. doi: 10.1186/s40959-021-00103-0.
Cardiooncology. 2021.
PMID: 33975650
Free PMC article.
Patients homozygous for the CBR3 V244M G allele (CBR3 V244) exhibited a further statistically significant decrease in LVEF at 6 months following DOX therapy in comparison with patients with heterozygous AG genotype. ...CONCLUSIONS: CBR3 V244M genotype status is associated …
Patients homozygous for the CBR3 V244M G allele (CBR3 V244) exhibited a further statistically significant decrease in LVEF at 6 month …