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FGF1 and insulin control lipolysis by convergent pathways.
Sancar G, Liu S, Gasser E, Alvarez JG, Moutos C, Kim K, van Zutphen T, Wang Y, Huddy TF, Ross B, Dai Y, Zepeda D, Collins B, Tilley E, Kolar MJ, Yu RT, Atkins AR, van Dijk TH, Saghatelian A, Jonker JW, Downes M, Evans RM. Sancar G, et al. Among authors: van zutphen t, van dijk th. Cell Metab. 2022 Jan 4;34(1):171-183.e6. doi: 10.1016/j.cmet.2021.12.004. Cell Metab. 2022. PMID: 34986332 Free PMC article.
Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer.
Suh JM, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin YQ, Yu RT, Liddle C, Atkins AR, Olefsky JM, Mohammadi M, Downes M, Evans RM. Suh JM, et al. Among authors: van dijk th. Nature. 2014 Sep 18;513(7518):436-9. doi: 10.1038/nature13540. Epub 2014 Jul 16. Nature. 2014. PMID: 25043058 Free PMC article.
Corrigendum: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer.
Suh JM, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin YQ, Yu RT, Liddle C, Atkins AR, Olefsky JM, Mohammadi M, Downes M, Evans RM. Suh JM, et al. Among authors: van dijk th. Nature. 2015 Apr 16;520(7547):388. doi: 10.1038/nature14304. Epub 2015 Mar 4. Nature. 2015. PMID: 25739500 No abstract available.
FXR overexpression alters adipose tissue architecture in mice and limits its storage capacity leading to metabolic derangements.
van Zutphen T, Stroeve JHM, Yang J, Bloks VW, Jurdzinski A, Roelofsen H, Huijkman NCA, van Dijk TH, Vonk RJ, van Deursen J, Staels B, Groen AK, Kuipers F. van Zutphen T, et al. Among authors: van deursen j, van dijk th. J Lipid Res. 2019 Sep;60(9):1547-1561. doi: 10.1194/jlr.M094508. Epub 2019 Jun 28. J Lipid Res. 2019. PMID: 31253637 Free PMC article.
Short-term protein restriction at advanced age stimulates FGF21 signalling, energy expenditure and browning of white adipose tissue.
Dommerholt MB, Blankestijn M, Vieira-Lara MA, van Dijk TH, Wolters H, Koster MH, Gerding A, van Os RP, Bloks VW, Bakker BM, Kruit JK, Jonker JW. Dommerholt MB, et al. Among authors: van os rp, van dijk th. FEBS J. 2021 Apr;288(7):2257-2277. doi: 10.1111/febs.15604. Epub 2020 Nov 9. FEBS J. 2021. PMID: 33089625 Free PMC article.
Increased insulin sensitivity and diminished pancreatic beta-cell function in DNA repair deficient Ercc1d/- mice.
Huerta Guevara AP, McGowan SJ, Kazantzis M, Stallons TR, Sano T, Mulder NL, Jurdzinski A, van Dijk TH, Eggen BJL, Jonker JW, Niedernhofer LJ, Kruit JK. Huerta Guevara AP, et al. Among authors: van dijk th. Metabolism. 2021 Apr;117:154711. doi: 10.1016/j.metabol.2021.154711. Epub 2021 Jan 23. Metabolism. 2021. PMID: 33493548 Free PMC article.
109 results