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Progress in antischistosomal N,N'-diaryl urea SAR.
Wu J, Wang C, Leas D, Vargas M, White KL, Shackleford DM, Chen G, Sanford AG, Hemsley RM, Davis PH, Dong Y, Charman SA, Keiser J, Vennerstrom JL. Wu J, et al. Bioorg Med Chem Lett. 2018 Feb 1;28(3):244-248. doi: 10.1016/j.bmcl.2017.12.064. Epub 2017 Dec 29. Bioorg Med Chem Lett. 2018. PMID: 29317164 Free PMC article.
Synthesis of 2-Azaadamantan-6-one: A Missing Isomer.
Wu J, Leas DA, Dong Y, Wang X, Ezell EL, Stack DE, Vennerstrom JL. Wu J, et al. ACS Omega. 2018 Sep 30;3(9):11362-11367. doi: 10.1021/acsomega.8b01819. Epub 2018 Sep 18. ACS Omega. 2018. PMID: 30288462 Free PMC article.
Inhibition of Cytomegalovirus Replication with Extended-Half-Life Synthetic Ozonides.
Wang Y, Mukhopadhyay R, Roy S, Kapoor A, Su YP, Charman SA, Chen G, Wu J, Wang X, Vennerstrom JL, Arav-Boger R. Wang Y, et al. Among authors: wu j. Antimicrob Agents Chemother. 2018 Dec 21;63(1):e01735-18. doi: 10.1128/AAC.01735-18. Print 2019 Jan. Antimicrob Agents Chemother. 2018. PMID: 30373792 Free PMC article.
SAR of a new antischistosomal urea carboxylic acid.
Wu J, Wang C, Häberli C, White KL, Shackleford DM, Chen G, Dong Y, Charman SA, Keiser J, Vennerstrom JL. Wu J, et al. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3648-3651. doi: 10.1016/j.bmcl.2018.10.039. Epub 2018 Oct 25. Bioorg Med Chem Lett. 2018. PMID: 30389288 Free PMC article.
Stochastic Protein Alkylation by Antimalarial Peroxides.
Jourdan J, Walz A, Matile H, Schmidt A, Wu J, Wang X, Dong Y, Vennerstrom JL, Schmidt RS, Wittlin S, Mäser P. Jourdan J, et al. Among authors: wu j. ACS Infect Dis. 2019 Dec 13;5(12):2067-2075. doi: 10.1021/acsinfecdis.9b00264. Epub 2019 Dec 2. ACS Infect Dis. 2019. PMID: 31626733
Structure-Activity Relationship of Antischistosomal Ozonide Carboxylic Acids.
Wu J, Wang X, Chiu FCK, Häberli C, Shackleford DM, Ryan E, Kamaraj S, Bulbule VJ, Wallick AI, Dong Y, White KL, Davis PH, Charman SA, Keiser J, Vennerstrom JL. Wu J, et al. J Med Chem. 2020 Apr 9;63(7):3723-3736. doi: 10.1021/acs.jmedchem.0c00069. Epub 2020 Mar 19. J Med Chem. 2020. PMID: 32134263 Free PMC article.
Diaryl Ureas as an Antiprotozoal Chemotype.
Leas DA, Sanford AG, Wu J, Cal M, Kaiser M, Wittlin S, Hemsley RM, Darner EB, Lui LM, Davis PH, Vennerstrom JL. Leas DA, et al. Among authors: wu j. ACS Infect Dis. 2021 Jun 11;7(6):1578-1583. doi: 10.1021/acsinfecdis.1c00135. Epub 2021 May 10. ACS Infect Dis. 2021. PMID: 33971090 Free PMC article.
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