Lewis LA - Search Results

1

Efficacy of an Experimental Gonococcal Lipooligosaccharide Mimitope Vaccine Requires Terminal Complement.

Lewis LA, Gulati S, Zelek WM, Morgan BP, Song WC, Zheng B, Nowak N, DeOliveira RB, Sanchez B, DeSouza Silva L, Schuurman J, Beurskens F, Ram S, Rice PA. Lewis LA, et al. J Infect Dis. 2022 May 16;225(10):1861-1864. doi: 10.1093/infdis/jiab630. J Infect Dis. 2022. PMID: 34971376 Free PMC article.

2

Enhanced factor H binding to sialylated Gonococci is restricted to the sialylated lacto-N-neotetraose lipooligosaccharide species: implications for serum resistance and evidence for a bifunctional lipooligosaccharide sialyltransferase in Gonococci.

Gulati S, Cox A, Lewis LA, Michael FS, Li J, Boden R, Ram S, Rice PA. Gulati S, et al. Among authors: lewis la. Infect Immun. 2005 Nov;73(11):7390-7. doi: 10.1128/IAI.73.11.7390-7397.2005. Infect Immun. 2005. PMID: 16239538 Free PMC article.

3

The meningococcal vaccine candidate GNA1870 binds the complement regulatory protein factor H and enhances serum resistance.

Madico G, Welsch JA, Lewis LA, McNaughton A, Perlman DH, Costello CE, Ngampasutadol J, Vogel U, Granoff DM, Ram S. Madico G, et al. Among authors: lewis la. J Immunol. 2006 Jul 1;177(1):501-10. doi: 10.4049/jimmunol.177.1.501. J Immunol. 2006. PMID: 16785547 Free PMC article.

4

Heptose I glycan substitutions on Neisseria gonorrhoeae lipooligosaccharide influence C4b-binding protein binding and serum resistance.

Ram S, Ngampasutadol J, Cox AD, Blom AM, Lewis LA, St Michael F, Stupak J, Gulati S, Rice PA. Ram S, et al. Among authors: lewis la. Infect Immun. 2007 Aug;75(8):4071-81. doi: 10.1128/IAI.01109-06. Epub 2007 May 25. Infect Immun. 2007. PMID: 17526744 Free PMC article.

5

Defining targets for complement components C4b and C3b on the pathogenic neisseriae.

Lewis LA, Ram S, Prasad A, Gulati S, Getzlaff S, Blom AM, Vogel U, Rice PA. Lewis LA, et al. Infect Immun. 2008 Jan;76(1):339-50. doi: 10.1128/IAI.00613-07. Epub 2007 Nov 5. Infect Immun. 2008. PMID: 17984207 Free PMC article.

6

Phosphoethanolamine substitution of lipid A and resistance of Neisseria gonorrhoeae to cationic antimicrobial peptides and complement-mediated killing by normal human serum.

Lewis LA, Choudhury B, Balthazar JT, Martin LE, Ram S, Rice PA, Stephens DS, Carlson R, Shafer WM. Lewis LA, et al. Infect Immun. 2009 Mar;77(3):1112-20. doi: 10.1128/IAI.01280-08. Epub 2008 Dec 29. Infect Immun. 2009. PMID: 19114544 Free PMC article.

7

Functional comparison of the binding of factor H short consensus repeat 6 (SCR 6) to factor H binding protein from Neisseria meningitidis and the binding of factor H SCR 18 to 20 to Neisseria gonorrhoeae porin.

Shaughnessy J, Lewis LA, Jarva H, Ram S. Shaughnessy J, et al. Among authors: lewis la. Infect Immun. 2009 May;77(5):2094-103. doi: 10.1128/IAI.01561-08. Epub 2009 Mar 9. Infect Immun. 2009. PMID: 19273554 Free PMC article.

8

The meningococcal vaccine candidate neisserial surface protein A (NspA) binds to factor H and enhances meningococcal resistance to complement.

Lewis LA, Ngampasutadol J, Wallace R, Reid JE, Vogel U, Ram S. Lewis LA, et al. PLoS Pathog. 2010 Jul 29;6(7):e1001027. doi: 10.1371/journal.ppat.1001027. PLoS Pathog. 2010. PMID: 20686663 Free PMC article.

9

Infections of people with complement deficiencies and patients who have undergone splenectomy.

Ram S, Lewis LA, Rice PA. Ram S, et al. Among authors: lewis la. Clin Microbiol Rev. 2010 Oct;23(4):740-80. doi: 10.1128/CMR.00048-09. Clin Microbiol Rev. 2010. PMID: 20930072 Free PMC article. Review.

10

Meningococcal group W-135 and Y capsular polysaccharides paradoxically enhance activation of the alternative pathway of complement.

Ram S, Lewis LA, Agarwal S. Ram S, et al. Among authors: lewis la. J Biol Chem. 2011 Mar 11;286(10):8297-8307. doi: 10.1074/jbc.M110.184838. Epub 2011 Jan 18. J Biol Chem. 2011. PMID: 21245150 Free PMC article.

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