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Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent manner.
Provine NM, Amini A, Garner LC, FitzPatrick MEB, Dold C, Silva Reyes L, Chinnakannan S, Oguti B, Raymond M, Troise F, Capone S, Folgori A, Barnes E, Rollier CS, Pollard AJ, Klenerman P. Provine NM, et al. Among authors: chinnakannan s. Eur J Immunol. 2022 May;52(5):835-837. doi: 10.1002/eji.202149367. Epub 2022 Jan 17. Eur J Immunol. 2022. PMID: 34958459 Free article.
Use of an Outbred Rat Hepacivirus Challenge Model for Design and Evaluation of Efficacy of Different Immunization Strategies for Hepatitis C Virus.
Atcheson E, Li W, Bliss CM, Chinnakannan S, Heim K, Sharpe H, Hutchings C, Dietrich I, Nguyen D, Kapoor A, Jarvis MA, Klenerman P, Barnes E, Simmonds P. Atcheson E, et al. Among authors: chinnakannan s. Hepatology. 2020 Mar;71(3):794-807. doi: 10.1002/hep.30894. Epub 2019 Oct 11. Hepatology. 2020. PMID: 31400152 Free PMC article.
MAIT cell activation augments adenovirus vector vaccine immunogenicity.
Provine NM, Amini A, Garner LC, Spencer AJ, Dold C, Hutchings C, Silva Reyes L, FitzPatrick MEB, Chinnakannan S, Oguti B, Raymond M, Ulaszewska M, Troise F, Sharpe H, Morgan SB, Hinks TSC, Lambe T, Capone S, Folgori A, Barnes E, Rollier CS, Pollard AJ, Klenerman P. Provine NM, et al. Among authors: chinnakannan s. Science. 2021 Jan 29;371(6528):521-526. doi: 10.1126/science.aax8819. Science. 2021. PMID: 33510029 Free PMC article.
Antibody testing for COVID-19: A report from the National COVID Scientific Advisory Panel.
Adams ER, Ainsworth M, Anand R, Andersson MI, Auckland K, Baillie JK, Barnes E, Beer S, Bell JI, Berry T, Bibi S, Carroll M, Chinnakannan SK, Clutterbuck E, Cornall RJ, Crook DW, de Silva T, Dejnirattisai W, Dingle KE, Dold C, Espinosa A, Eyre DW, Farmer H, Fernandez Mendoza M, Georgiou D, Hoosdally SJ, Hunter A, Jefferey K, Kelly DF, Klenerman P, Knight J, Knowles C, Kwok AJ, Leuschner U, Levin R, Liu C, López-Camacho C, Martinez J, Matthews PC, McGivern H, Mentzer AJ, Milton J, Mongkolsapaya J, Moore SC, Oliveira MS, Pereira F, Perez E, Peto T, Ploeg RJ, Pollard A, Prince T, Roberts DJ, Rudkin JK, Sanchez V, Screaton GR, Semple MG, Slon-Campos J, Skelly DT, Smith EN, Sobrinodiaz A, Staves J, Stuart DI, Supasa P, Surik T, Thraves H, Tsang P, Turtle L, Walker AS, Wang B, Washington C, Watkins N, Whitehouse J; National COVID Testing Scientific Advisory Panel. Adams ER, et al. Among authors: chinnakannan sk. Wellcome Open Res. 2020 Jun 11;5:139. doi: 10.12688/wellcomeopenres.15927.1. eCollection 2020. Wellcome Open Res. 2020. PMID: 33748431 Free PMC article.
T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses.
Ogbe A, Kronsteiner B, Skelly DT, Pace M, Brown A, Adland E, Adair K, Akhter HD, Ali M, Ali SE, Angyal A, Ansari MA, Arancibia-Cárcamo CV, Brown H, Chinnakannan S, Conlon C, de Lara C, de Silva T, Dold C, Dong T, Donnison T, Eyre D, Flaxman A, Fletcher H, Gardner J, Grist JT, Hackstein CP, Jaruthamsophon K, Jeffery K, Lambe T, Lee L, Li W, Lim N, Matthews PC, Mentzer AJ, Moore SC, Naisbitt DJ, Ogese M, Ogg G, Openshaw P, Pirmohamed M, Pollard AJ, Ramamurthy N, Rongkard P, Rowland-Jones S, Sampson O, Screaton G, Sette A, Stafford L, Thompson C, Thomson PJ, Thwaites R, Vieira V, Weiskopf D, Zacharopoulou P; Oxford Immunology Network Covid-19 Response T Cell Consortium; Oxford Protective T Cell Immunology for COVID-19 (OPTIC) Clinical Team; Turtle L, Klenerman P, Goulder P, Frater J, Barnes E, Dunachie S. Ogbe A, et al. Among authors: chinnakannan s. Nat Commun. 2021 Apr 6;12(1):2055. doi: 10.1038/s41467-021-21856-3. Nat Commun. 2021. PMID: 33824342 Free PMC article.
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern.
Skelly DT, Harding AC, Gilbert-Jaramillo J, Knight ML, Longet S, Brown A, Adele S, Adland E, Brown H; Medawar Laboratory Team; Tipton T, Stafford L, Mentzer AJ, Johnson SA, Amini A; OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group; Tan TK, Schimanski L, Huang KA, Rijal P; PITCH (Protective Immunity T cells in Health Care Worker) Study Group; C-MORE/PHOSP-C Group; Frater J, Goulder P, Conlon CP, Jeffery K, Dold C, Pollard AJ, Sigal A, de Oliveira T, Townsend AR, Klenerman P, Dunachie SJ, Barnes E, Carroll MW, James WS. Skelly DT, et al. Nat Commun. 2021 Aug 17;12(1):5061. doi: 10.1038/s41467-021-25167-5. Nat Commun. 2021. PMID: 34404775 Free PMC article.
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